Pharmacophore model of ALS inhibitors by DISCO method

In this paper Pharmacophore Models of the interaction of four varieties of ALS inhibitors by distance comparison (DISCO) method with unknown three-dimensional structure of the receptor are reported, The Model not only conforms to our research requirement, but also helps to find a lot of unexpected biological information, which provides a theoretical guidance for the further design of new and more active ALS inhibitory herbicides and the active cavity simulation of its receptors.