Dynamin and receptor-mediated endocytosis

被引：60
作者：
Damke, H
机构：
来源：
FEBS LETTERS | 1996年 / 389卷 / 01期
关键词：
receptor-mediated endocytosis; clathrin-coated vesicle; dynamin; GTPase;
D O I：
10.1016/0014-5793(96)00517-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The internalization of receptor-hound ligands involves concentration of cell surface receptors in specialized areas of the plasma membrane and subsequent formation of clathrin-coated vesicles, The complex process of invagination, constriction and budding of clathrin-coated vesicles employs the coordinated actions of several proteins, This review is focused on the GTPase dynamin, which plays a key role in the constriction of coated pits.
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页码：48 / 51
页数：4
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