Etiopathogenesis of Canine Hip Dysplasia, Prevalence, and Genetics

被引:39
|
作者
King, Michael D. [1 ]
机构
[1] Canada West Vet Specialists & Crit Care Hosp, Dept Surg, 1988 Kootenay St, Vancouver, BC V5M 4Y3, Canada
关键词
Pathogenesis; Genetic; Dysplasia; Prevalence; QUANTITATIVE TRAIT LOCI; LIMITED FOOD-CONSUMPTION; DEGENERATIVE JOINT DISEASE; MILITARY WORKING DOGS; LABRADOR-RETRIEVERS; FEMORAL-HEAD; RISK-FACTORS; ORTHOPEDIC FOUNDATION; COXOFEMORAL JOINTS; DISTRACTION INDEX;
D O I
10.1016/j.cvsm.2017.03.001
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
First identified in 1935, canine hip dysplasia is thought to be the most common orthopedic condition diagnosed in the dog. It is most prevalent in large and giant breed dogs, with a complex polygenic mode of inheritance, and relatively low heritability. External factors including caloric intake when growing have a significant effect on phenotypic expression. Initial joint laxity progresses to osteoarthritis due to subluxation and abnormal wearing. Selective breeding programs to attempt to decrease prevalence have shown modest results so far.
引用
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页码:753 / +
页数:16
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