A Comparative Study of Two Matrix Factorization Methods Applied to the Classification of Gene Expression Data

被引:0
|
作者
Nikulin, Vladimir [1 ]
Huang, Tian-Hsiang [2 ]
McLachlan, Geoffrey J. [1 ,3 ]
机构
[1] Univ Queensland, Dept Math, Brisbane, Qld, Australia
[2] Natl Cheng Kung Univ, Inst Informat Management, Tainan, Taiwan
[3] Univ Queensland, Inst Mol Biosci, Brisbane, Qld, Australia
关键词
MICROARRAY DATA;
D O I
暂无
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
In microarray data analysis, dimension reduction is an important consideration in the construction of a successful classification algorithm. As an alternative to feature selection, we use a well-known matrix factorisation method. For example, we can employ the popular singular-value decomposition (SVD) or nonnegative matrix factorization. In this paper, we consider a novel algorithm for gradient-based matrix factorisation (GMF). We compare GMF and SVD in their application to five gene expression datasets. The experimental results show that our method is faster, more stable, and sensitive.
引用
收藏
页码:618 / 621
页数:4
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