A review of the pharmacokinetic properties of SYM-1219, a single oral dose granule formulation containing 2 g of secnidazole, for the treatment of bacterial vaginosis

被引：2

作者：

Pentikis, H. ^{[1
]}

Adetoro, N. ^{[1
]}

机构：

[1] Symbiomix Therapeut LLC, Newark, NJ USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2017年 / 217卷 / 06期

关键词：

D O I：

10.1016/j.ajog.2017.08.086

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

引用

页码：715 / 716

页数：5

共 14 条

[1] A phase 3 randomized, double-blind, placebo-controlled study to confirm the efficacy and safety of a single, oral dose of SYM-1219, a granule formulation containing 2 grams of secnidazole, for the treatment of bacterial vaginosis
Schwebke, J.
Morgan, F.
Koltun, W.
Pentikis, H.
Adetoro, N.
Braun, C.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2016, 215 (06) : 821 - 822
[2] A phase 2 randomized, double-blind, placebo-controlled study to evaluate the effectiveness and safety of single, oral doses of SYM-1219, a granule formulation containing 1 and 2 gram doses of secnidazole, for the treatment of women with bacterial vaginosis
Hillier, S. L.
Morgan, F. G.
Waldbaum, A. S.
Schwebke, J. R.
Nyirjesy, P.
Adetoro, N.
Braun, C. J.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2015, 213 (06) : 885 - 885
[3] Efficacy and safety of single dose of oral secnidazole 2 g in treatment of bacterial vaginosis: A systematic review and meta-analysis
Elghazalya, Shrouk M.
Hamam, Khaled M.
Badawy, Marwa M.
Agha, Nadim Aiman Yakoub
Samy, Ahmed
Abbas, Ahmed M.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2019, 238 : 125 - 131
[4] An Integrated Efficacy and Safety Analysis of Single-Dose Secnidazole 2 g in the Treatment of Bacterial Vaginosis
Pentikis, Helen
Adetoro, Nikki
Tipping, Diane
Levy, Sharon
REPRODUCTIVE SCIENCES, 2020, 27 (02) : 523 - 528
[5] An Integrated Efficacy and Safety Analysis of Single-Dose Secnidazole 2 g in the Treatment of Bacterial Vaginosis
Helen Pentikis
Nikki Adetoro
Diane Tipping
Sharon Levy
Reproductive Sciences, 2020, 27 : 523 - 528
[6] Lack of a Pharmacokinetic Interaction Between SYM-1219 Granules Containing 2 Grams of Secnidazole and a Combined Oral Contraceptive in a Phase 1, Randomized, Open-Label Study in Healthy Female Volunteers
Helen S. Pentikis
Nikki Adetoro
Carol J. Braun
Advances in Therapy, 2016, 33 : 2229 - 2241
[7] Lack of a Pharmacokinetic Interaction Between SYM-1219 Granules Containing 2 Grams of Secnidazole and a Combined Oral Contraceptive in a Phase 1, Randomized, Open-Label Study in Healthy Female Volunteers
Pentikis, Helen S.
Adetoro, Nikki
Braun, Carol J.
ADVANCES IN THERAPY, 2017, 33 (12) : 2229 - 2241
[8] An integrated efficacy and safety analysis of single-dose secnidazole 2 g granules in the treatment of bacterial vaginosis from pivotal phase 2 and phase 3 trials
Pentikis, H. S.
Adetoro, N.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2018, 219 (06) : 647 - 648
[9] A phase-3, double-blind, placebo-controlled study of the effectiveness and safety of single oral doses of secnidazole 2 g for the treatment of women with bacterial vaginosis
Schwebke, Jane R.
Morgan, Franklin G., Jr.
Koltun, William
Nyirjesy, Paul
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2017, 217 (06) : 678.e1 - 678.e9
[10] A Phase 3, Multicenter, Prospective, Open-Label Study to Evaluate the Safety of a Single Dose of Secnidazole 2 g for the Treatment of Women and Postmenarchal Adolescent Girls with Bacterial Vaginosis
Chavoustie, Steven E.
Gersten, Janet K.
Samuel, Milroy J.
Schwebke, Jane R.
JOURNAL OF WOMENS HEALTH, 2018, 27 (04) : 492 - 497

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