DISCOVERY OF A LIVER-SPECIFIC ENHANCER-PROMOTER ELEMENT IN THE 3′UTR OF THE WILD-TYPE AAV2 GENOME PROVIDES NOVEL INSIGHTS INTO AAV VECTOR SAFETY IN THE HUMAN LIVER

被引：0

作者：

Logan, Grant J. ^{[1
,2
]}

Dane, Allison P. ^{[1
,2
,10
]}

Hallwirth, Claus V. ^{[1
,2
]}

Smyth, Christine M. ^{[1
,2
]}

Wilkie, Emilie E. ^{[3
]}

Amaya, Anais K. ^{[1
,2
]}

Zhu, Erhua ^{[1
,2
]}

Khandekar, Neeta ^{[1
,2
]}

Ginn, Samantha L. ^{[1
,2
]}

Liao, Sophia ^{[1
,2
]}

Cunningham, Sharon C. ^{[1
,2
]}

Sasaki, Natsuki ^{[1
,2
]}

Tam, Patrick P. L. ^{[4
]}

Russell, David W. ^{[5
,6
]}

Lisowski, Leszek ^{[7
,8
]}

Alexander, Ian E. ^{[1
,2
,9
]}

机构：

[1] Univ Sydney, Gene Therapy Res Unit, Childrens Med Res Inst, Sydney, NSW, Australia

[2] Univ Sydney, Sydney Childrens Hosp Network, Sydney, NSW, Australia

[3] Univ Sydney, Bioinformat, Sydney, NSW, Australia

[4] Univ Sydney, Childrens Med Res Inst, Embryol Units, Sydney, NSW, Australia

[5] Univ Washington, Dept Med, Seattle, WA USA

[6] Univ Washington, Dept Biochem, Seattle, WA 98195 USA

[7] Univ Sydney, Childrens Med Res Inst, Translat Vectorol Grp, Sydney, NSW, Australia

[8] Mil Inst Hyg & Epidemiol MIHiE, Pulawy, Poland

[9] Univ Sydney, Discipline Child & Adolescent Hlth, Westmead, NSW, Australia

[10] UCL, Inst Canc, Dept Haematol, London, England

来源：

JOURNAL OF GENE MEDICINE | 2018年 / 20卷 / 01期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页数：2

共 2 条