Inoculum effect and bactericidal activity of cefditoren and other antibiotics against Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis

被引:19
|
作者
Soriano, F [1 ]
Coronel, P [1 ]
Gimeno, M [1 ]
Jimenez, M [1 ]
GarciaCorbeira, P [1 ]
FernandezRoblas, R [1 ]
机构
[1] TEDEC MEIJI FARMA SA,DEPT RES & DEV,MADRID,SPAIN
关键词
D O I
10.1007/BF01691969
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The inoculum effect on minimum inhibitory and minimum bactericidal concentrations of cefditoren, benzylpenicillin, ampicillin, cefotaxime, ceftriaxone, and meropenem against six clinical isolates each of Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis was studied using inocula of approximately 10(4) to 10(5) and 10(7) to 10(8) cfu/ml. Vancomycin was also studied against Streptococcus pneumoniae. The inoculum effect was observed only with benzylpenicillin and ampicillin against five of six strains of Haemophilus influenzae. All antibiotics tested were bactericidal.
引用
收藏
页码:761 / 763
页数:3
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