Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation

被引：4

作者：

Doroftei, Bogdan ^{[1
,2
,3
]}

Zlei, Mihaela ^{[3
,4
,5
]}

Simionescu, Gabriela ^{[2
,3
]}

Maftei, Radu ^{[2
,3
]}

Cumpata, Simona ^{[3
]}

Emerson, Geraldine ^{[3
]}

机构：

[1] Univ Med & Pharm, Dept Obstet & Gynecol, Iasi, Romania

[2] Teaching Hosp Obgyn Cuza Voda, Iasi, Romania

[3] Origyn Fertil Ctr, Iasi, Romania

[4] Reg Inst Oncol, Iasi, Romania

[5] Reg Inst Oncol, Mol Biol Lab, Iasi 700483, Romania

来源：

REPRODUCTIVE HEALTH | 2015年 / 12卷

关键词：

Globozoospermia; Artificial Oocyte Activation; IMSI; ROUND-HEADED SPERMATOZOA; FERTILIZATION; ZETA; PLC;

D O I：

10.1186/s12978-015-0031-x

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment at oocyte retrieval only round headed sperm were observed. Considering the high risk of a complete failure to fertilize from IMSI the couple gave written informed consent to the use of oocyte activation media post IMSI. One embryo fertilized, developed to a hatching blastocyst and was transferred resulting in an ongoing pregnancy. This successful outcome shows the use of IMSI is useful in the evaluation of total globozooozpermia and therefore aids in the justification of the use of oocyte activation media.

引用

页数：4

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