Toca 511 & Toca FC: Evaluation of Durable Response Rate in the Post-Resection Setting and Association with Survival in Patients with Recurrent High Grade Glioma

被引：0

作者：

Cloughesy, Timothy ^{[1
]}

Landolfi, Joseph ^{[2
]}

Vogelbaum, Michael ^{[3
]}

Ostertag, Derek ^{[4
]}

Elder, Bradley ^{[5
]}

Carter, Bob ^{[6
]}

Chen, Clark ^{[7
]}

Kalkanis, Steven ^{[8
]}

Kesari, Santosh ^{[9
]}

Lai, Albert ^{[1
]}

Lee, Ian ^{[8
]}

Liau, Linda ^{[1
]}

Nghiemphu, Phioanh ^{[1
]}

Piccioni, David ^{[10
]}

Accomando, William ^{[4
]}

Diago, Oscar ^{[4
]}

Hogan, Daniel ^{[4
]}

Jolly, Douglas ^{[4
]}

Wood, Katie ^{[4
]}

Kheoh, Thian ^{[4
]}

Gruber, Harry ^{[4
]}

Das, Asha ^{[4
]}

Walbert, Tobias ^{[8
]}

机构：

[1] Univ Calif Los Angeles, Los Angeles, CA USA

[2] New Jersey Neurosci Inst, Edison, NJ USA

[3] Cleveland Clin, Lerner Coll Med, Cleveland, OH 44106 USA

[4] Tocagen Inc, San Diego, CA USA

[5] Ohio State Univ, Columbus, OH 43210 USA

[6] MGH, Boston, MA USA

[7] Univ Minnesota, Minneapolis, MN USA

[8] Henry Ford Hosp, Detroit, MI 48202 USA

[9] John Wayne Canc Inst, Santa Monica, CA USA

[10] UCSD, San Diego, CA USA

来源：

NEUROLOGY | 2018年 / 90卷

关键词：

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

S23.006

引用

页数：4

共 42 条

[1] TOCA 511 & TOCA FC VERSUS STANDARD OF CARE IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA
Cloughesy, Timothy
Petrecca, Kevin
Walbert, Tobias
Butowski, Nicholas
Salacz, Michael
Perry, James
Damek, Denise
Bota, Daniela
Bettegowda, Chetan
Zhu, Jay-Jiguang
Iwamoto, Fabio
Placantonakis, Dimitris
Martinez, Nina
Elder, J. Bradley
Kaptain, George
Cachia, David
Moshel, Yaron
Brem, Steven
Picconi, David
Nam Tran
Nam, Do-Hyun
Park, Chul-Kee
Landolfi, Joseph
Tran, David
Ramakrishna, Rohan
Fink, Karen
Heros, Deborah
Zadeh, Gelareh
Nicholas, Garth
Mehta, Vivek
Robins, H. Ian
Chen, Clark
Pitz, Marshall
Heth, Jason
Nagpal, Seema
Pearlman, Michael
Ahluwalia, Manmeet
Mohile, Nimish
Merrell, Ryan
Schiff, David
Thompson, Reid
Davis, Raphael
Macdonald, David
Kheoh, Thian
Kabbinavar, Fairooz
Lossos, Alexander
Vogelbaum, Michael
NEURO-ONCOLOGY, 2019, 21 : 284 - 284
[2] Durable responses observed in recurrent high-grade glioma (rHGG) with Toca 511 and Toca FC treatment
Cloughesy, Timothy F.
Landolfi, Joseph
Vogelbaum, Michael
Ostertag, Derek
Elder, Bradley
Carter, Bob
Chen, Clark C.
Kalkanis, Steven
Kesari, Santosh
Lai, Albert
Lee, Ian
Liau, Linda
Mikkelsen, Tom
Nghiemphu, Leia
Piccioni, David
Accomando, William
Diago, Oscar
Hogan, Daniel
Jolly, Douglas J.
Wood, Katie
Gruber, Harry
Das, Asha
Walbert, Tobias
MOLECULAR CANCER THERAPEUTICS, 2018, 17 (01)
[3] Toca 511 Followed by Toca FC in Subjects with Recurrent High Grade Glioma (HGG)
Aghi, Manish K.
Vogelbaum, Michael
Cloughesy, Timothy
Kesari, Santosh
Portnow, Jana
Ostertag, Derek
Keller, Mary Rose
Chu, Alice
Skillings, Jamey
Kaptain, George
JOURNAL OF NEUROSURGERY, 2016, 124 (04) : A1154 - A1154
[4] Durable complete responses in some recurrent highgrade glioma patients treated with Toca 511+Toca FC
Cloughesy, Timothy F.
Landolfi, Joseph
Vogelbaum, Michael A.
Ostertag, Derek
Elder, James B.
Bloomfield, Stephen
Carter, Bob
Chen, Clark C.
Kalkanis, Steven N.
Kesari, Santosh
Lai, Albert
Lee, Ian Y.
Liau, Linda M.
Mikkelsen, Tom
Nghiemphu, Phioanh
Piccioni, David
Accomando, William
Diago, Oscar R.
Hogan, Daniel J.
Gammon, Dawn
Kasahara, Noriyuki
Kheoh, Thian
Jolly, Douglas J.
Gruber, Harry E.
Das, Asha
Walbert, Tobias
NEURO-ONCOLOGY, 2018, 20 (10) : 1383 - 1392
[5] EXTENDED BENEFITS IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA THAT CONTINUOUSLY RECEIVE TOCA FC AFTER TOCA 511 TREATMEN
Walbert, Tobias
Damek, Denise
Martinez, Nina L.
Piccioni, David
Singer, Samuel
Cloughesy, Timothy
NEURO-ONCOLOGY, 2021, 23 : 58 - 59
[6] DURABLE RESPONSES OBSERVED IN IDH1 WILDTYPE AND MUTANT RECURRENT HIGH GRADE GLIOMA (rHGG) WITH TOCA 511 & TOCA FC TREATMENT
Cloughesy, Timothy
Landolfi, Joseph
Vogelbaum, Michael
Ostertag, Derek
Elder, Bradley
Carter, Bob
Chen, Clark
Kalkanis, Steven
Lai, Albert
Mikkelsen, Tom
Nghiemphu, Phioanh
Piccioni, David
Accomando, William
Diago, Oscar
Hogan, Daniel
Jolly, Douglas
Wood, Katie
Yang, Liqiang
Gruber, Harry
Das, Asha
Walbert, Tobias
NEURO-ONCOLOGY, 2017, 19 : 26 - 26
[7] EVIDENCE SUPPORTINGMECHANISMOFACTIONAND DRUG ACTIVITY IN PHASE I TRIAL OF PATIENTS WITH RECURRENT HIGH GRADE GLIOMA ADMINISTERED TOCA 511 AT SURGICAL RESECTION FOLLOWED BY TOCA FC
Cloughesy, Timothy F.
Liau, Linda M.
Chiocca, E. Antonio
Jolly, Douglas J.
Robbins, Joan M.
Ostertag, Derek
Ibanez, Carlos E.
Gruber, Harry E.
Kasahara, Noriyuki
Vogelbaum, Michael A.
Kesari, Santosh
Mikkelsen, Tom
Kalkanis, Steven
Landolfi, Joseph
Bloomfield, Stephen
Foltz, Greg
Pertschuk, Dan
NEURO-ONCOLOGY, 2013, 15 : 69 - 69
[8] IMMUNOLOGIC TRENDS ASSOCIATED WITH PATIENT OUTCOMES IN A PHASE 1 CLINICAL TRIAL OF TOCA 511 AND TOCA FC IN RECURRENT HIGH GRADE GLIOMA
Accomando, William
Cloughesy, Timothy
Kalkanis, Steven
Mikkelsen, Tom
Landolfi, Joseph
Carter, Bob
Chen, Clark
Vogelbaum, Michael
Elder, James
Piccioni, David
Walbert, Tobias
Hogan, Daniel
Diago, Oscar
Gammon, Dawn
Haghighi, Ali
Kheoh, Thian
Gruber, Harry
Jolly, Douglas
Ostertag, Derek
NEURO-ONCOLOGY, 2018, 20 : 6 - 7
[9] Evaluation of durable response rate in the post-resection setting and association with survival in patients with recurrent high grade glioma who received vocimagene amiretroprepvec and 5-fluorocytosine treatment
Carter, Bob S.
Cloughesy, Timothy
Landolfi, Joseph
Vogelbaum, Michael
Elder, Brad
Chen, Clark
Kalkanis, Steven
Kesari, Santosh
Lee, Ian
Piccioni, David
Walbert, Tobias
JOURNAL OF NEUROSURGERY, 2018, 128 (04) : 49 - 49
[10] Durable complete responses observed in IDH1 mutated high grade glioma at first recurrence undergoing treatment with Toca 511 and Toca FC.
Cloughesy, Timothy Francis
Ostertag, Derek
Landolfi, Joseph C.
Walbert, Tobias
Vogelbaum, Michael A.
Elder, J. Bradley
Bloomfield, Steven
Carter, Bob
Chen, Clark
Kalkanis, Steven N.
Kesari, Santosh
Lai, Albert
Lee, Ian
Liau, Linda M.
Mikkelsen, Tom
Nghiemphu, Phioanh Leia
Piccioni, David Eric
Jolly, Douglas J.
Gruber, Harry E.
Das, Asha
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35

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