Catalytic enantioselective protonation of a samarium enolate with fluorous chiral and achiral proton sources in fluorous biphasic systems

被引：63
|
作者：
Takeuchi, S
Nakamura, Y
Ohgo, Y
Curran, DP
机构：
[1] Niigata Coll Pharm, Niigata 9502081, Japan
[2] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 47期
基金：
美国国家卫生研究院;
关键词：
fluorine and compounds; asymmetric; catalysis; protonation;
D O I：
10.1016/S0040-4039(98)01900-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Enantioselectivities near maximum values were obtained in the catalytic reaction by a rapid addition of a fluorous achiral alcohol (Rfh(3)C-OH) to the reaction mixture:for DHPEX in Rfh(3)C-OH/THF solid-liquid biphase system and for a fluorous chiral alcohol in THF/FC-72 liquid-liquid biphase system. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8691 / 8694
页数：4
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