Serum syndecan-1 in patients with newly diagnosed monoclonal proteinemia

被引：0
|
作者：
Schaar, Cees G. [1 ]
Vermeer, Henricus J. [2 ]
Wijermans, Pierre W. [3 ]
Huisman, Wim [4 ]
le Cessie, Saskia [5 ]
Kluin-Nelemans, Hanneke C. [6 ]
机构：
[1] Comprehens Canc Ctr West, Leiden, Netherlands
[2] Haga Hosp, Dept Clin Chem, The Hague, Netherlands
[3] Haga Hosp, Dept Hematol, The Hague, Netherlands
[4] Med Ctr Haaglanden, Dept Clin Chem, The Hague, Netherlands
[5] Leiden Univ, Dept Med Stat, Med Ctr, Leiden, Netherlands
[6] Univ Med Ctr Groningen, Dept Hematol, POB 30001, NL-9700 RB Groningen, Netherlands
来源：
HAEMATOLOGICA | 2005年 / 90卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Serum syndecan- 1 was investigated in 189 patients with newly diagnosed monoclonal proteinemia [the diagnoses were multiple myeloma (66), monoclonal gammopathies of undetermined significance (MGUS; n=54), provisional MGUS (no bone marrow examination performed; n=69)] and 36 controls. Syndecan-1 levels ranged widely between all diagnostic categories and were of limited discriminatory value (sensitivity 68%, specificity 78%) in patients with newly diagnosed monoclonal proteinemia.
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页码：1437 / 1438
页数：2
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