HORMONE REPLACEMENT THERAPY;
EARLY ESTROGEN PREVENTION;
INTIMA-MEDIA THICKNESS;
CORONARY-HEART-DISEASE;
BREAST-CANCER RISK;
HOT FLASHES;
VENOUS THROMBOEMBOLISM;
POSTMENOPAUSAL WOMEN;
BLACK COHOSH;
PROGESTERONE;
D O I:
10.4158/EP171828.PS
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
This American Association of Clinical Endocrinologists (AACE)/American College of Endocrinology (ACE) Position Statement is designed to update the previous menopause clinical practice guidelines published in 2011 but does not replace them. The current document reviews new clinical trials published since then as well as new information regarding possible risks and benefits of therapies available for the treatment of menopausal symptoms. AACE reinforces the recommendations made in its previous guidelines and provides additional recommendations on the basis of new data. A summary regarding this position statement is listed below: New information available from randomized clinical trials and epidemiologic studies reported after 2011 was critically reviewed. No previous recommendations from the 2011 menopause clinical practice guidelines have been reversed or changed. Newer information enhances AACE's guidance for the use of hormone therapy in different subsets of women. Newer information helps to support the use of various types of estrogens, selective estrogen-receptor modulators (SERMs), and progesterone, as well as the route of delivery. Newer information supports the previous recommendation against the use of bioidentical hormones. The use of nonhormonal therapies for the symptomatic relief of menopausal symptoms is supported. Newer information enhances AACE's guidance for the use of hormone therapy in different subsets of women. Newer information helps to support the use of various types of estrogens, SERMs, and progesterone, as well as the route of delivery. Newer information supports the previous recommendation against the use of bioidentical hormones. The use of nonhormonal therapies for the symptomatic relief of menopausal symptoms is supported.
机构:
Harvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
Beth Israel Deaconess Med Ctr, Boston, MA 02215 USAHarvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
Hennessey, James V.
Garber, Jeffrey R.
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
Harvard Vanguard Med Associates, Boston, MA USAHarvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
Garber, Jeffrey R.
Woeber, Kenneth A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Dept Med, Sch Med, Div Endocrinol, San Francisco, CA USAHarvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
Woeber, Kenneth A.
Cobin, Rhoda
论文数: 0引用数: 0
h-index: 0
机构:
Icahn Sch Med Mt Sinai, Dept Med, Div Endocrinol, New York, NY 10029 USAHarvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
Cobin, Rhoda
Klein, Irwin
论文数: 0引用数: 0
h-index: 0
机构:
NYU, Sch Med, Dept Med, Div Endocrinol, New York, NY USAHarvard Univ, Sch Med, Dept Med, Div Endocrinol, Boston, MA USA
机构:
Eastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Vinik, Aaron I.
Camacho, Pauline M.
论文数: 0引用数: 0
h-index: 0
机构:
Loyola Univ, Med Ctr, Dept Endocrinol Diabet & Metab, 2160 S 1st Ave, Maywood, IL 60153 USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Camacho, Pauline M.
Davidson, Jaime A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Chicago, Pritzker Sch Med, Chicago, IL 60637 USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Davidson, Jaime A.
Handelsman, Yehuda
论文数: 0引用数: 0
h-index: 0
机构:
Metab Inst Amer, Tarzana, CA USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Handelsman, Yehuda
Lando, Howard M.
论文数: 0引用数: 0
h-index: 0
机构:
George Washington Univ, Alexandria, VA USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Lando, Howard M.
Leddy, Anne L.
论文数: 0引用数: 0
h-index: 0
机构:
Riverside Reg Med Ctr, Newport News, VA USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Leddy, Anne L.
Reddy, Sethu K.
论文数: 0引用数: 0
h-index: 0
机构:
Cleveland Clin, Dept Endocrinol Diabet & Metab, Cleveland, OH 44106 USAEastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Reddy, Sethu K.
Cook, Richard
论文数: 0引用数: 0
h-index: 0
机构:Eastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Cook, Richard
Spallone, Vicenza
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h-index: 0
机构:Eastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Spallone, Vicenza
Tesfaye, Solomon
论文数: 0引用数: 0
h-index: 0
机构:Eastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
Tesfaye, Solomon
Ziegler, Dan
论文数: 0引用数: 0
h-index: 0
机构:Eastern Virginia Med Sch, Dept Med, Strelitz Diabet & Neuroendocrine Unit, Norfolk, VA 23501 USA
机构:
Mayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Hurley, Daniel L.
Binkley, Neil
论文数: 0引用数: 0
h-index: 0
机构:
Univ Wisconsin, Sch Med & Publ Hlth, Div Endocrinol, Madison, WI USA
Univ Wisconsin, Sch Med & Publ Hlth, Div Geriatr, Madison, WI USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Binkley, Neil
Camacho, Pauline M.
论文数: 0引用数: 0
h-index: 0
机构:
Loyola Univ, Loyola Univ Med Ctr, Osteoporosis & Metab Bone Dis Ctr, Maywood, IL 60153 USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Camacho, Pauline M.
Diab, Dima L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Cincinnati, Div Endocrinol, Cincinnati, OH USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Diab, Dima L.
Kennel, Kurt A.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Div Endocrinol & Metab, Rochester, MN USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Kennel, Kurt A.
Malabanan, Alan
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Med Sch, Div Endocrinol Diabet & Metab, Beth Israel Deaconess Med Ctr, Boston, MA USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Malabanan, Alan
Tangpricha, Vin
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Sch Med, Dept Med, Div Endocrinol Metab & Lipids, Atlanta, GA USA
Atlanta VA Med Ctr, Div Endocrinol, Decatur, GA USAMayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
机构:
Metab Inst Amer, Tarzana, CA USA
Amer Coll Endocrinol, Tarzana, CA USAMetab Inst Amer, Tarzana, CA USA
Handelsman, Yehuda
Henry, Robert R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Med, San Diego, CA 92103 USA
VA San Diego Healthcare Syst, Sect Diabet Endocrinol & Metab, San Diego, CA USAMetab Inst Amer, Tarzana, CA USA
Henry, Robert R.
Bloomgarden, Zachary T.
论文数: 0引用数: 0
h-index: 0
机构:
Icahn Sch Med Mt Sinai, New York, NY 10029 USAMetab Inst Amer, Tarzana, CA USA
Bloomgarden, Zachary T.
Dagogo-Jack, Sam
论文数: 0引用数: 0
h-index: 0
机构:
Univ Tennessee, Hlth Sci Ctr, Div Endocrinol Diabet & Metab, Memphis, TN USAMetab Inst Amer, Tarzana, CA USA
Dagogo-Jack, Sam
DeFronzo, Ralph A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Hlth Sci Ctr San Antonio, Diabet Div, San Antonio, TX 78229 USAMetab Inst Amer, Tarzana, CA USA
DeFronzo, Ralph A.
Einhorn, Daniel
论文数: 0引用数: 0
h-index: 0
机构:
Amer Coll Endocrinol, La Jolla, CA USA
Amer Assoc Clin Endocrinologists, La Jolla, CA USA
Scripps Whittier Diabet Inst, La Jolla, CA USA
UCSD, Med, La Jolla, CA USA
Diabet & Endocrine Associates, Journal Diabet, La Jolla, CA USAMetab Inst Amer, Tarzana, CA USA
Einhorn, Daniel
Ferrannini, Ele
论文数: 0引用数: 0
h-index: 0
机构:
CNR, Inst Clin Physiol, Internal Med, Via Savi 8, I-56100 Pisa, ItalyMetab Inst Amer, Tarzana, CA USA
Ferrannini, Ele
Fonseca, Vivian A.
论文数: 0引用数: 0
h-index: 0
机构:
Tulane Univ, Hlth Sci Ctr, Med & Pharmacol, New Orleans, LA 70118 USA
Tulane Univ, Hlth Sci Ctr, Diabet, New Orleans, LA 70118 USA
Tulane Univ, Hlth Sci Ctr, Endocrinol Sect, New Orleans, LA 70118 USAMetab Inst Amer, Tarzana, CA USA
Fonseca, Vivian A.
Garber, Alan J.
论文数: 0引用数: 0
h-index: 0
机构:
Baylor Coll Med, Dept Med, Houston, TX 77030 USA
Baylor Coll Med, Dept Biochem, Houston, TX 77030 USA
Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USAMetab Inst Amer, Tarzana, CA USA
Garber, Alan J.
Grunberger, George
论文数: 0引用数: 0
h-index: 0
机构:
Amer Assoc Clin Endocrinologists, Bloomfield Hills, MI USA
Grunberger Diabet Inst, Bloomfield Hills, MI USA
Wayne State Univ, Sch Med, Internal Med & Mol Med & Genet, Detroit, MI USA
Oakland Univ, William Beaumont Sch Med, Internal Med, Rochester, MI 48063 USA
Charles Univ Prague, Fac Med 1, Internal Med, Prague, Czech RepublicMetab Inst Amer, Tarzana, CA USA
Grunberger, George
LeRoith, Derek
论文数: 0引用数: 0
h-index: 0
机构:
Mt Sinai Sch Med, Div Endocrinol Diabet & Bone Dis, Res, New York, NY USAMetab Inst Amer, Tarzana, CA USA
LeRoith, Derek
Umpierrez, Guillermo E.
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Sch Med, Med, Atlanta, GA USA
Grady Hlth Syst, Endocrinol Sect, Atlanta, GA USAMetab Inst Amer, Tarzana, CA USA
Umpierrez, Guillermo E.
Weir, Matthew R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Maryland, Sch Med, Div Nephrol, Baltimore, MD 21201 USA
Univ Maryland, Sch Med, Med, Baltimore, MD 21201 USAMetab Inst Amer, Tarzana, CA USA
机构:
AMCR Inst, Escondido, CA USA
Univ Calif San Diego, Sch Med, La Jolla, CA 92093 USAAMCR Inst, Escondido, CA USA
Bailey, Timothy S.
Grunberger, George
论文数: 0引用数: 0
h-index: 0
机构:
Grunberger Diabet Inst, Bloomfield Hills, MI USA
Wayne State Univ, Sch Med, Internal Med & Mol Med & Genet, Detroit, MI 48202 USA
Oakland Univ, William Beaumont Sch Med, Internal Med, Bloomfield Hills, MI USAAMCR Inst, Escondido, CA USA
Grunberger, George
Bode, Bruce W.
论文数: 0引用数: 0
h-index: 0
机构:
Atlanta Diabet Associates, Atlanta, GA USA
Emory Univ, Sch Med, Med, Atlanta, GA USAAMCR Inst, Escondido, CA USA
Bode, Bruce W.
Handelsman, Yehuda
论文数: 0引用数: 0
h-index: 0
机构:
Metab Inst Amer, Tarzana, CA USA
Amer Coll Endocrinol, Tarzana, CA USAAMCR Inst, Escondido, CA USA
Handelsman, Yehuda
Hirsch, Irl B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Washington, Sch Med, Med, Seattle, WA USAAMCR Inst, Escondido, CA USA
Hirsch, Irl B.
Jovanovic, Lois
论文数: 0引用数: 0
h-index: 0
机构:
Sansum Diabet Res Inst, Santa Barbara, CA USA
Univ So Calif, Keck Sch Med, Med, Los Angeles, CA 90033 USA
Santa Barbara Cty Hlth Care Serv, Santa Barbara, CA USA
Univ Calif Santa Barbara, Biomol Sci & Engn & Chem Engn, Santa Barbara, CA 93106 USAAMCR Inst, Escondido, CA USA
Jovanovic, Lois
Roberts, Victor Lawrence
论文数: 0引用数: 0
h-index: 0
机构:
Univ Cent Florida, Coll Med, Internal Med, Orlando, FL 32816 USAAMCR Inst, Escondido, CA USA
Roberts, Victor Lawrence
Rodbard, David
论文数: 0引用数: 0
h-index: 0
机构:
Biomed Informat Consultants LLC, Potomac, MD USAAMCR Inst, Escondido, CA USA
Rodbard, David
Tamborlane, William V.
论文数: 0引用数: 0
h-index: 0
机构:
Yale Univ, Sch Med, Pediat Endocrinol, New Haven, CT USAAMCR Inst, Escondido, CA USA
Tamborlane, William V.
Walsh, John
论文数: 0引用数: 0
h-index: 0
机构:
AMCR Inst, Escondido, CA USAAMCR Inst, Escondido, CA USA