Immuno-nephelometric determination of group streptococcal anti-streptolysin O titres (ASOT) from dried blood spots: Method for validating a new assay

被引:3
|
作者
Joseph, John [3 ]
Kent, Neil [3 ]
Bowen, Asha [1 ,2 ,4 ,5 ]
Hart, Julie [3 ]
Sheel, Meru [2 ]
Wardrop, Robert [6 ]
Abbs, Sam [3 ]
Bazely, Scott [5 ]
Rybak, Monika [3 ]
机构
[1] Charles Darwin Univ, Menzies Sch Hlth Res, Darwin, NT, Australia
[2] Univ Western Australia, Telethon Kids Inst, Wesfarmers Ctr Vaccines & Infect Dis, Nedlands, WA, Australia
[3] QE2 Med Ctr Redev, PathWest Lab Med, Nedlands, WA, Australia
[4] Princess Margaret Hosp Children, Subiaco, WA, Australia
[5] Univ Western Australia, Nedlands, WA, Australia
[6] Gilbert Bain Hosp NHS Shetland, Lerwick, Scotland
关键词
ACUTE RHEUMATIC-FEVER; HEART-DISEASE; HIGH-RATES; VIRUS; COMMUNITIES; PHARYNGITIS; INFECTION; AUSTRALIA; HEPATITIS; SAMPLE;
D O I
10.1016/j.jim.2017.05.009
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This study was designed to determine the sensitivity and reproducibility of recovering anti-streptolysin 0 titres (ASOT) from dried,blood spot (DBS) samples, a methodologic subcomponent of the penicillin pharmacokinetic studies in children receiving secondary prophylaxis with intramuscular benzathine penicillin for acute rheumatic fever. Crown Copyright (C) 2017 Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:59 / 65
页数:7
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