Obesity is underdiagnosed, hampering system-based health promotion and research. Our objective was to develop and validate a claims-based risk model to identify obese persons using medical diagnosis and prescription records. We conducted a cross-sectional analysis of de-identified claims data from enrollees of 3 Blue Cross Blue Shield plans who completed a health risk assessment capturing height and weight. The final sample of 71,057 enrollees was randomly split into 2 subsamples for development and validation of the obesity risk model. Using the Johns Hopkins Adjusted Clinical Groups case-mix/predictive risk methodology, we categorized study members' diagnosis (ICD) codes. Logistic regression was used to determine which claims-based risk markers were associated with a body mass index (BMI) >= 35 kg/m(2). The sensitivities of the scores >= 90(th) percentile to detect obesity were 26% to 33%, while the specificities were >90%. The areas under the receiver operator curve ranged from 0.67 to 0.73. In contrast, a diagnosis of obesity or an obesity medication alone had very poor sensitivity (10% and 1%, respectively); the obesity risk model identified an additional 22% of obese members. Varying the percentile cut-point from the 70(th) to the 99(th) percentile resulted in positive predictive values ranging from 15.5 to 59.2. An obesity risk score was highly specific for detecting a BMI >= 35 kg/m(2) and substantially increased the detection of obese members beyond a provider-coded obesity diagnosis or medication claim. This model could be used for obesity care management and health promotion or for obesity-related research. (Population Health Management 2010;13:201-207)
机构:
Washington Univ, Sch Med, Div Gen Med Sci, Dept Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Div Gen Med Sci, Dept Med, St Louis, MO 63110 USA
Deshpande, Anjali D.
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Schootman, Mario
Mayer, Allese
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St Louis Univ, Dept Epidemiol, Coll Publ Hlth & Social Justice, St Louis, MO 63103 USAWashington Univ, Sch Med, Div Gen Med Sci, Dept Med, St Louis, MO 63110 USA
机构:
Merck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Bali, V.
Weaver, J.
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Merck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Weaver, J.
Turzhitsky, V.
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Merck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Turzhitsky, V.
Schelfhout, J.
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Merck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Schelfhout, J.
Paudel, M.
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Optum Insight, Hlth Econ & Outcomes Res HEOR, Eden Prairie, MN USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Paudel, M.
Hulbert, E.
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Optum Insight, Hlth Econ & Outcomes Res HEOR, Eden Prairie, MN USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Hulbert, E.
Peterson-Brandt, J.
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Optum Insight, Hlth Econ & Outcomes Res HEOR, Eden Prairie, MN USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Peterson-Brandt, J.
Hertzberg, J.
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Optum Insight, Optum Enterprise Analyt OEA, Eden Prairie, MN USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Hertzberg, J.
Kelly, N. R.
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Optum Insight, Optum Enterprise Analyt OEA, Eden Prairie, MN USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
Kelly, N. R.
Patel, R. H.
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Optum Insight, Optum Enterprise Analyt OEA, Eden Prairie, MN USAMerck & Co Inc, Ctr Observat & Real World Evidence CORE, Kenilworth, NJ USA
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Albert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Pavlovic, Jelena M.
Yu, Justin S.
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Allergan Plc, Irvine, CA USA
Novartis Pharmaceut, E Hanover, NJ USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Yu, Justin S.
Silberstein, Stephen D.
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Jefferson Headache Ctr, Philadelphia, PA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Silberstein, Stephen D.
Reed, Michael L.
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Vedanta Res, Chapel Hill, NC USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Reed, Michael L.
Kawahara, Steve H.
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DaVita Med Grp, El Segundo, CA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Kawahara, Steve H.
Cowan, Robert P.
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Stanford Univ, Sch Med, Stanford, CA 94305 USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Cowan, Robert P.
Dabbous, Firas
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机构:Albert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Dabbous, Firas
Campbell, Karen L.
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Allergan Plc, Irvine, CA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Campbell, Karen L.
Shewale, Anand R.
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Allergan Plc, Irvine, CA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Shewale, Anand R.
Pulicharam, Riya
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DaVita Med Grp, El Segundo, CA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Pulicharam, Riya
Kowalski, Jonathan W.
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Allergan Plc, Irvine, CA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Kowalski, Jonathan W.
Viswanathan, Hema N.
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Allergan Plc, Irvine, CA USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
Viswanathan, Hema N.
Lipton, Richard B.
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Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10461 USAAlbert Einstein Coll Med, Montefiore Headache Ctr, Dept Neurol, 1250 Waters Pl,Tower 2,8th Floor, Bronx, NY 10461 USA
机构:
Brigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, 1620 Tremont St,Suite 3030, Boston, MA 02120 USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Lee, Hemin
He, Mengdong
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Brigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, 1620 Tremont St,Suite 3030, Boston, MA 02120 USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
He, Mengdong
Cho, Soo-Kyung
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Brigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Hanyang Univ Hosp Rheumat Dis, Dept Rheumatol, Seoul, South KoreaBrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Cho, Soo-Kyung
Bessette, Lily
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Brigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, 1620 Tremont St,Suite 3030, Boston, MA 02120 USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Bessette, Lily
Tong, Angela Y.
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Brigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, 1620 Tremont St,Suite 3030, Boston, MA 02120 USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Tong, Angela Y.
Merola, Joseph F.
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Harvard Med Sch, Dept Dermatol, Brigham & Womens Hosp, Boston, MA 02120 USA
Harvard Med Sch, Brigham & Womens Hosp, Div Rheumatol Inflammat & Immun, Boston, MA 02120 USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Merola, Joseph F.
Wegrzyn, Lani R.
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AbbVie Inc, Global Epidemiol Pharmacovigilance & Patient Safe, N Chicago, IL USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Wegrzyn, Lani R.
Kilpatrick, Ryan D.
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AbbVie Inc, Global Epidemiol Pharmacovigilance & Patient Safe, N Chicago, IL USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Kilpatrick, Ryan D.
Kim, Seoyoung C.
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Brigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA
Harvard Med Sch, Brigham & Womens Hosp, Div Rheumatol Inflammat & Immun, Boston, MA 02120 USABrigham & Womens Hosp, Div Pharmacoepidemiol & Pharmacoecon, 1620 Tremont St,Suite 3030, Boston, MA 02120 USA