Voltammetric Determination of N-Actylcysteine Using Modified Multiwall Carbon Nanotubes Paste Electrode

被引：0
|
作者：
Karimi-Maleh, Hassan [1 ]
Keyvanfard, Mohsen [1 ]
Alizad, Khadijeh [1 ]
Fouladgar, Masoud [2 ]
Beitollahi, Hadi [3 ]
Mokhtari, Ali [4 ]
Gholami-Orimi, Fathali [5 ]
机构：
[1] Islamic Azad Univ, Majlesi Branch, Dept Chem, Esfahan, Iran
[2] Islamic Azad Univ, Falavarjan Branch, Dept Biochem, Falavarjan, Iran
[3] Int Ctr Sci High Technol & Environm Sci, Res Inst Environm Sci, Dept Environm, Kerman, Iran
[4] Golestan Univ, Dept Engn & Technol, Aliabad Katool, Iran
[5] Islamic Azad Univ, Qaemshahr Branch, Dept Chem, Qaemshahr, Iran
来源：
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2011年 / 6卷 / 12期
关键词：
N-Acetylcysteine; Ferrocene; carbon nanotubes paste electrode; voltammetry; ELECTROCATALYTIC DETERMINATION; PHARMACEUTICAL FORMULATIONS; P-AMINOPHENOL; SPECTROPHOTOMETRIC DETERMINATION; SELECTIVE DETERMINATION; HUMAN PLASMA; FOLIC-ACID; ACETYLCYSTEINE; SENSOR; NOREPINEPHRINE;
D O I：
暂无
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
A ferrocene modified carbon nanotubes paste electrode (FCMCNTPE) was constructed and used as a fast and sensitive tool for the determination of N-acetylcysteine (NAC) at trace level. It has been shown by direct current cyclic voltammetry and double step chronoamperometry that this sensor can catalyze the oxidation of NAC in phosphate buffer solution (PBS) and produces a sharp oxidation peak current. Linear calibration ranges were 1.0-400.0 mu mol L-1 with detections limit of 0.6 mu mol L-1 for differential pulse voltammetry. Finally, the sensor was also examined as a selective, simple and precise new electrochemical sensor for the determination of NAC in real samples such as drug, serum and urine.
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页码：6141 / 6150
页数：10
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