Lighter general Anesthesia causes less decrease in arterial pressure induced by epinephrine scalp infiltration during neurosurgery

被引:11
|
作者
Yang, Pan-jun
Liu, Jin [1 ]
Duan, Man-lin
Zhou, Zhi-qiang
Li, Wei-yan
Xu, Jian-guo
机构
[1] Sichuan Univ, W China Hosp, Dept Anesthesiol, Chengdu 610041, Peoples R China
[2] Nanjing Univ, Sch Med, Dept Anesthesiol, Nanjing 210008, Peoples R China
关键词
epinephrine; infiltration; hypotension; general anesthesia; craniotomy;
D O I
10.1097/ANA.0b013e31812f6c32
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Scalp infiltration with epinephrine-containing lidocaine solution can elicit significant hypotension before craniotomy under general anesthesia.. A prospective randomized controlled study was designed to observe whether a lighter depth of general anesthesia could prevent the unintentional hypotension induced by the epinephrine scalp infiltration during neurosurgery or not. Fifty patients undergoing scheduled neurosurgery involving craniotomy were randomly allocated into 2 groups. After anesthesia induction, anesthesia was maintained with propofol 2 mu g/mL and rimifentanil 2 ng/mL by target-controlled infusion in group 1, and propofol 4 mu g/mL and rimifentanil 4 ng/mL in group 2 (control group), respectively. All the patients received epinephrine scalp infiltration with 1% lidocaine 16mL containing epinephrine 5 mu g/mL. Mean arterial pressure (MAP) and heart rate were recorded at 30-second interval from the baseline to 5 minutes after the beginning of local infiltration. Bispectral index readings indicated group I had the lighter general anesthesia than group 2 (P < 0.05). MAP was higher (P < 0.05) and heart rate was lower (P < 0.05) at 1.5 minutes time point in group I than group 2. The mean percentage of maximal decrease in MAP was group 1 (13%) < group 2 (24%) (P < 0.05). The mean percentage of maximal increase in MAP was group 1 (10%) > group 2 (4%) without significant difference (P > 0.05). The results implied that keeping a lighter general anesthesia caused less decrease in arterial blood pressure and was a relative effective method to prevent hypotension episode induced by epinephrine scalp infiltration.
引用
收藏
页码:263 / 267
页数:5
相关论文
共 46 条
  • [1] Epinephrine Infiltration of Scalp or Nasal Mucosa Induces What Kind of Changes in Blood Pressure Under General Anesthesia: Hypertension or Hypotension?
    Yang, Jian-jun
    Yu, Hong-mei
    Peng, Yong G.
    JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY, 2010, 22 (01) : 79 - 80
  • [2] Late arterial insufficiency in a toe-to-finger transplantation following infiltration anesthesia with articaine plus epinephrine during septorhinoplasty
    Kostakoglu, N
    Kayikcioglu, A
    PLASTIC AND RECONSTRUCTIVE SURGERY, 1998, 101 (04) : 1146 - 1146
  • [3] Epinephrine infiltration on nasal field causes significant hemodynamic changes: Hypotension episode monitored by impedance-cardiography under general anesthesia
    Yang, Jian-jun
    Zheng, Jun
    Liu, Hong-jun
    Liu, Yu-xiu
    Shen, Jin-Chun
    Zhou, Zhi-qiang
    JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, 2006, 9 (02): : 190 - 197
  • [4] Norepinephrine reduces arterial compliance less than phenylephrine when treating general anesthesia-induced arterial hypotension
    Vallee, F.
    Passouant, O.
    Le Gall, A.
    Joachim, J.
    Mateo, J.
    Mebazaa, A.
    Gayat, E.
    ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2017, 61 (06) : 590 - 600
  • [5] A micromechanical device that monitors arterial pressure during general anesthesia and in intensive care units
    Andreeva, A. V.
    Luchinin, V. V.
    Kuzmina, K. A.
    Klyavinek, A. S.
    Karelov, A. E.
    17TH RUSSIAN YOUTH CONFERENCE ON PHYSICS AND ASTRONOMY (PHYSICA.SPB/2014), 2015, 661
  • [6] EFFECTS OF COMMON RESPIRATORY PHENOMENA DURING GENERAL ANESTHESIA ON ARTERIAL BLOOD PRESSURE AND PULSE
    JONES, RE
    HELRICH, M
    ECKENHOFF, JE
    ANESTHESIOLOGY, 1956, 17 (02) : 325 - 333
  • [7] Pulmonary Artery Pressure and Variations in Arterial Blood Pressure During the Induction Period of General Anesthesia in Elderly Patients
    Liu, Yulin
    Chen, Fei
    Zhao, Weibing
    Zhu, Ying
    JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2021, 31 (01): : 8 - 13
  • [8] Data-based Pharmacodynamic Modeling for BIS and Mean Arterial Pressure Prediction during General Anesthesia
    Aubouin-Pairault, Bob
    Fiacchini, Mirko
    Dang, Thao
    2023 EUROPEAN CONTROL CONFERENCE, ECC, 2023,
  • [9] Prophylactic Antibiotic Administration Induced Bronchospasm as Increased Airway Pressure During General Anesthesia
    Kuo, Yi-Min
    Ting, Chien-Kun
    Wang, Yu-Chieh
    Chang, Wen-Kuei
    Wu, Hsin-Lun
    Chan, Kwok-Hon
    Chen, Pin-Tarng
    JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, 2010, 73 (02) : 72 - 77
  • [10] Preoperative ketamine attenauted tourniquet-induced systemic arterial pressure increase in patients under general anesthesia
    Satsumae, T
    Yamaguchi, H
    Sakaguchi, M
    Yamashita, S
    Yamamoto, S
    ANESTHESIOLOGY, 1999, 91 (3A) : U247 - U247