Activated protein C inhibits lipopolysaccharide-induced anandamide and 2-arachidonoylglycerol generation In Vitro and In Vivo

被引:0
|
作者
Maruyama, Ikuro [1 ]
Wang, Yin [1 ]
Liu, Yan [1 ]
Kawahara, Koichi [1 ]
Yamakuchi, Munekazu [1 ]
Hashiguchi, Teruto [1 ]
Obata, Toru [2 ]
机构
[1] Kagoshima Univ, Grad Sch Med & Dent Sci, Lab & Vasc Med, Kagoshima, Japan
[2] Jikei Univ, Sch Med, Dept Mol Cell Biol, Minato Ku, Tokyo, Japan
关键词
D O I
10.1182/blood.V110.11.1754.1754
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1754
引用
收藏
页码:521A / 521A
页数:1
相关论文
共 50 条
  • [1] Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration
    Hansen, HH
    Schmid, PC
    Bittigau, P
    Lastres-Becker, I
    Berrendero, F
    Manzanares, J
    Ikonomidou, C
    Schmid, HHO
    Fernández-Ruiz, JJ
    Hansen, HS
    JOURNAL OF NEUROCHEMISTRY, 2001, 78 (06) : 1415 - 1427
  • [2] Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
    Mauro Maccarrone
    Silvia Rossi
    Monica Bari
    Valentina De Chiara
    Filomena Fezza
    Alessandra Musella
    Valeria Gasperi
    Chiara Prosperetti
    Giorgio Bernardi
    Alessandro Finazzi-Agrò
    Benjamin F Cravatt
    Diego Centonze
    Nature Neuroscience, 2008, 11 : 152 - 159
  • [3] Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
    Maccarrone, Mauro
    Rossi, Silvia
    Bari, Monica
    De Chiara, Valentina
    Fezza, Filomena
    Musella, Alessandra
    Gasperi, Valeria
    Prosperetti, Chiara
    Bernardi, Giorgio
    Finazzi-Agro, Alessandro
    Cravatt, Benjamin F.
    Centonze, Diego
    NATURE NEUROSCIENCE, 2008, 11 (02) : 152 - 159
  • [4] Activated protein C (APC) inhibits lipopolysaccharide (LPS)-induced anandamide and 2-arachidonylglycerol generation in vitro and in vivo:: A possible mechanism of improving of severe septic patients by APC.
    Maruyama, I
    Wang, Y
    Liu, Y
    Yamaji, K
    Sarker, KP
    Abeyama, K
    Wada, H
    Hashiguchi, T
    BLOOD, 2003, 102 (11) : 93B - 93B
  • [5] Rapamycin inhibits lipopolysaccharide-induced neuroinflammation in vitro and in vivo
    Mengke, Na-Shun
    Hu, Bei
    Han, Qian-Peng
    Deng, Yi-Yu
    Fang, Ming
    Xie, Di
    Li, Ang
    Zeng, Hong-Ke
    MOLECULAR MEDICINE REPORTS, 2016, 14 (06) : 4957 - 4966
  • [6] Licochalcone A Inhibits Lipopolysaccharide-Induced Inflammatory Response in Vitro and in Vivo
    Chu, Xiao
    Ci, Xinxin
    Wei, Miaomiao
    Yang, Xiaofeng
    Cao, Qingjun
    Guan, Mingfeng
    Li, Hongyu
    Deng, Yanhong
    Feng, Haihua
    Deng, Xuming
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, 60 (15) : 3947 - 3954
  • [7] LL202 inhibits lipopolysaccharide-induced angiogenesis in vivo and in vitro
    Gao, Yuan
    Zhao, Kai
    Huang, Yujie
    Zhou, Yuxin
    Li, Zhiyu
    Guo, Ruichen
    Guo, Qinglong
    Wu, Yulin
    Lu, Na
    RSC ADVANCES, 2014, 4 (110) : 64565 - 64576
  • [8] Spontaneous Acetylcholine Release Potentiation Induced by 2-Arachidonoylglycerol and Anandamide in Mouse Motor Synapses
    Tarasova E.O.
    Khotkina N.A.
    Gaydukov A.E.
    Balezina O.P.
    Moscow University Biological Sciences Bulletin, 2021, 76 (1) : 1 - 6
  • [9] Acanthopanax trifoliatus inhibits lipopolysaccharide-induced inflammatory response in vitro and in vivo
    Chien, Tzu-Mei
    Hsieh, Po-Chow
    Huang, Shyh-Shyun
    Deng, Jeng-Shyan
    Ho, Yu-Ling
    Chang, Yuan-Shiun
    Huang, Guan-Jhong
    KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2015, 31 (10): : 499 - 509
  • [10] Activated protein C inhibits adrenomedullin induction and prevents lipopolysaccharide-induced hypotension in rats.
    Gupta, A
    Berg, DT
    Grinnell, BW
    CRITICAL CARE MEDICINE, 2005, 33 (12) : A142 - A142