Patients' preferences for breast reconstruction: A discrete choice experiment

被引:34
|
作者
Damen, Tim H. C. [1 ]
de Bekker-Grob, Esther W. [2 ]
Mureau, Marc A. M. [1 ]
Menke-Pluijmers, Marian B. [3 ]
Seynaeve, Caroline [4 ]
Hofer, Stefan O. P. [1 ,5 ]
Essink-Bot, Marie-Louise [6 ]
机构
[1] Erasmus Univ, Med Ctr, Dept Plast & Reconstruct Surg, NL-3000 CA Rotterdam, Netherlands
[2] Erasmus MC, Dept Publ Hlth, Rotterdam, Netherlands
[3] Family Canc Clin, Erasmus MC Daniel den Hoed Canc Ctr, Dept Surg Oncol, Rotterdam, Netherlands
[4] Family Canc Clin, Erasmus MC Daniel den Hoed Canc Ctr, Dept Med Oncol, Rotterdam, Netherlands
[5] Univ Toronto, Univ Hlth Network, Div Plast Surg, Toronto, ON, Canada
[6] Univ Amsterdam, Acad Med Ctr, Dept Social Med, NL-1105 AZ Amsterdam, Netherlands
关键词
Breast cancer; Genetic predisposition; Mastectomy; Breast reconstruction; Patient preference; Utility; EPIGASTRIC PERFORATOR FLAP; DRUG-TREATMENT; LONG-TERM; MASTECTOMY; SURGERY; COMPLICATIONS; DETERMINANTS; SATISFACTION; OUTCOMES; WOMEN;
D O I
10.1016/j.bjps.2010.04.030
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Patients' preferences are important determinants in the decision for a specific type of breast reconstruction (BR). Understanding their considerations in the decision for a specific type of BR can contribute to further improvement in patient counselling. We explored patients' preferences for three BR modalities in a discrete choice experiment (DCE). Methods: We approached 386 patients who had previously undergone a therapeutic (n = 309) or prophylactic (n = 79) mastectomy, of whom 247 had also undergone a BR. These women were asked to choose between hypothetical BR profiles that were characterised by six treatment attributes: (1) material used for reconstruction, (2) number and duration of operations, (3) short-term complication rate, (4) long-term complication rate, (5) aesthetic result and (6) waiting time. The relative importance of attributes and trade-offs that the patients were willing to make among them were analysed using a multinomial logit regression model. Results: The overall response rate was 71%. All treatment characteristics proved important for patients to make their choices. Respondents generally expressed a preference for autologous material and an excellent aesthetic result, which had the biggest positive effect on preferences. Complication rates of 20-30% had a similar negative effect. In this DCE, autologous free flap BR fitted in best with patients' preferences. Conclusions: Our study provides insight into the relative weight patients place on various aspects of BR and trade-offs they make among BR characteristics. In addition to understanding patients' considerations, professional assessment of the technical feasibility, acceptable risks and obtainable aesthetic result of different techniques will always remain crucial in deciding which technique is best suited for an individual patient. (C) 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:75 / 83
页数:9
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