Detection of Japanese encephalitis virus antibodies in bats in southern China

被引:34
|
作者
Cui, Jie [2 ,3 ]
Counor, Dorian [1 ]
Shen, Di [3 ]
Sun, Guya [1 ]
He, Hongxuan [4 ]
Deubel, Vincent [1 ]
Zhang, Shuyi [2 ]
机构
[1] Chinese Acad Sci, Emergency Viruses Inst Pasteur Shanghai, Shanghai 200025, Peoples R China
[2] E China Normal Univ, Sch Life Sci, Shanghai 200062, Peoples R China
[3] Hebei Normal Univ, Coll Life Sci, Shijiazhuang 050016, Peoples R China
[4] Chinese Acad Sci, Inst Zool, Natl Res Ctr Wildlife Born Dis, Beijing 100101, Peoples R China
来源
关键词
D O I
10.4269/ajtmh.2008.78.1007
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In this study, 336 bats of eight species were collected during 2004-2007 in six provinces of Southern China. Antibodies against Japanese encephalitis virus (JEV) were detected by ELISA in 43 of 336 (12.8%) serum samples. Among those ELISA-positive samples, 11 serum samples had neutralizing antibodies against JEV. No JEV was detected in brain and liver samples using specific real-time reverse transcriptase-polymerase chain reaction. This is the first report of JEV neutralizing antibodies in bats in China, which reinforces that bats can be involved in the life cycle of this virus.
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页码:1007 / 1011
页数:5
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