Contralateral hip fractures and other osteoporosis-related fractures in hip fracture patients: incidence and risk factors. An observational cohort study of 1,229 patients

被引:41
|
作者
Vochteloo, Anne J. H. [1 ,2 ]
van der Burg, Boudewijn L. S. Borger [3 ]
Roling, Maarten A. [1 ]
van Leeuwen, Diederik H. [1 ]
van den Berg, Peter [1 ]
Niggebrugge, Arthur H. P. [4 ]
de Vries, Mark R. [5 ]
Tuinebreijer, Wim E. [6 ]
Bloem, Rolf M. [1 ]
Nelissen, Rob G. H. H. [2 ]
Pilot, Peter [1 ]
机构
[1] Reinier de Graaf Grp, Dept Orthopaed, NL-2600 GA Delft, Netherlands
[2] Leiden Univ, Dept Orthopaed, Med Ctr, Leiden, Netherlands
[3] Rijnland Hosp, Dept Surg, Leiderdorp, Netherlands
[4] Bronovo Hosp, Dept Surg, The Hague, Netherlands
[5] Reinier de Graaf Grp, Dept Surg, NL-2600 GA Delft, Netherlands
[6] Erasmus MC, Dept Surg Traumatol, Univ Med Ctr, Rotterdam, Netherlands
关键词
Hip fracture; Contralateral; Bilateral; Osteoporosis; Risk factors; RANDOMIZED-TRIAL; NONVERTEBRAL FRACTURES; VERTEBRAL FRACTURES; BONE-DENSITY; WOMEN; ALENDRONATE; RISEDRONATE; 1ST; EPIDEMIOLOGY; MEN;
D O I
10.1007/s00402-012-1520-9
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
To report risk factors, 1-year and overall risk for a contralateral hip and other osteoporosis-related fractures in a hip fracture population. An observational study on 1,229 consecutive patients of 50 years and older, who sustained a hip fracture between January 2005 and June 2009. Fractures were scored retrospectively for 2005-2008 and prospectively for 2008-2009. Rates of a contralateral hip and other osteoporosis-related fractures were compared between patients with and without a history of a fracture. Previous fractures, gender, age and ASA classification were analysed as possible risk factors. The absolute risk for a contralateral hip fracture was 13.8 %, for one or more osteoporosis-related fracture(s) 28.6 %. First-, second- and third-year risk for a second hip fracture was 2, 1 and 0 %. Median (IQR) interval between both hip fractures was 18.5 (26.6) months. One-year incidence of other fractures was 6 %. Only age was a risk factor for a contralateral hip fracture, hazard ratio (HR) 1.02 (1.006-1.042, p = 0.008). Patients with a history of a fracture (33.1 %) did not have a higher incidence of fractures during follow-up (16.7 %) than patients without fractures in their history (14 %). HR for a contralateral hip fracture for the fracture versus the non-fracture group was 1.29 (0.75-2.23, p = 0.360). The absolute risk of a contralateral hip fracture after a hip fracture is 13.8 %, the 1-year risk was 2 %, with a short interval between the 2 hip fractures. Age was a risk factor for sustaining a contralateral hip fracture; a fracture in history was not.
引用
收藏
页码:1191 / 1197
页数:7
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