Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates

被引:109
|
作者
Gardimalla, HMR
Mandal, D
Stevens, PD
Yen, M
Gao, Y
机构
[1] So Illinois Univ, Dept Chem & Biochem, Carbondale, IL 62901 USA
[2] So Illinois Univ, Mat Technol Ctr, Carbondale, IL 62901 USA
关键词
D O I
10.1039/b504128g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.
引用
收藏
页码:4432 / 4434
页数:3
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