Improved procedures for the synthesis of (S)-2-[N-(N′-benzylprolyl)amino]benzophenone (BPB) and Ni(II) complexes of Schiff's bases derived from BPB and amino acids

被引：134

作者：

Belokon', YN ^{[1
]}

Tararov, VI ^{[1
]}

Maleev, VI ^{[1
]}

Savel'eva, TF ^{[1
]}

Ryzhov, MG ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Organoelement Cpds, Moscow 117813, Russia

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 23期

关键词：

D O I：

10.1016/S0957-4166(98)00449-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(S)-N-Benzylproline (BP) was obtained by the reaction of (S)-proline and benzylchloride in high chemical yield (89%). (S)-2-[N-(N'-Benzylprolyl)amino]benzophenone (BPB) was synthesized in amounts greater than 100 g by the SOCl2 promoted condensation of BP with 2-aminobenzophenone (yield 82%). Ni(IT) complexes of Schiff's bases derived from BPB and amino acids were prepared by an improved procedure involving the use of KOH as a base and MeOH as solvent (yield 90-91%). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4249 / 4252

页数：4

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