Driven polymer translocation in good and bad solvent: Effects of hydrodynamics and tension propagation

被引:13
|
作者
Moisio, J. E. [1 ]
Piili, J. [2 ]
Linna, R. P. [2 ]
机构
[1] GE Healthcare, Kuortaneenkatu 2, FI-00510 Helsinki, Finland
[2] Aalto Univ, Dept Comp Sci, POB 15400, FI-00076 Aalto, Finland
关键词
MOLECULAR-DYNAMICS; DNA TRANSLOCATION; NANOPORE; MODEL;
D O I
10.1103/PhysRevE.94.022501
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We investigate the driven polymer translocation through a nanometer-scale pore in the presence and absence of hydrodynamics both in good and bad solvent. We present our results on tension propagating along the polymer segment on the cis side that is measured for the first time using our method that works also in the presence of hydrodynamics. For simulations we use stochastic rotation dynamics, also called multiparticle collision dynamics. We find that in the good solvent the tension propagates very similarly whether hydrodynamics is included or not. Only the tensed segment is by a constant factor shorter in the presence of hydrodynamics. The shorter tensed segment and the hydrodynamic interactions contribute to a smaller friction for the translocating polymer when hydrodynamics is included, which shows as smaller waiting times and a smaller exponent in the scaling of the translocation time with the polymer length. In the bad solvent hydrodynamics has a minimal effect on polymer translocation, in contrast to the good solvent, where it speeds up translocation. We find that under bad-solvent conditions tension does not spread appreciably along the polymer. Consequently, translocation time does not scale with the polymer length. By measuring the effective friction in a setup where a polymer in free solvent is pulled by a constant force at the end, we find that hydrodynamics does speed up collective polymer motion in the bad solvent even more effectively than in the good solvent. However, hydrodynamics has a negligible effect on the motion of individual monomers within the highly correlated globular conformation on the cis side and hence on the entire driven translocation under bad-solvent conditions.
引用
收藏
页数:10
相关论文
共 18 条
  • [1] Polymer translocation induced by a bad solvent
    Loerscher, Christopher
    Ala-Nissila, Tapio
    Bhattacharya, Aniket
    PHYSICAL REVIEW E, 2011, 83 (01):
  • [2] Driven polymer translocation into a channel: Isoflux tension propagation theory and Langevin dynamics simulations
    Sarabadani, Jalal
    Metzler, Ralf
    Ala-Nissila, Tapio
    PHYSICAL REVIEW RESEARCH, 2022, 4 (03):
  • [3] Iso-flux tension propagation theory of driven polymer translocation: The role of initial configurations
    Sarabadani, Jalal
    Ikonen, Timo
    Ala-Nissila, Tapio
    JOURNAL OF CHEMICAL PHYSICS, 2014, 141 (21):
  • [4] Quantification of tension to explain bias dependence of driven polymer translocation dynamics
    Suhonen, P. M.
    Piili, J.
    Linna, R. P.
    PHYSICAL REVIEW E, 2017, 96 (06)
  • [5] Polymer translocation: effects of periodically driven confinement
    Dwivedi, Manish
    Singh, Swarn Lata
    Kumar, Sanjay
    SOFT MATTER, 2024, 20 (11) : 2455 - 2463
  • [6] Effects of solvent quality and non-equilibrium conformations on polymer translocation
    Kwon, Seulki
    Sung, Bong June
    JOURNAL OF CHEMICAL PHYSICS, 2018, 149 (24):
  • [7] Polydispersity effects in dilute polymer solutions in the good-solvent regime
    Pelissetto, Andrea
    MACROMOLECULES, 2006, 39 (12) : 4184 - 4194
  • [8] Influence of non-universal effects on dynamical scaling in driven polymer translocation
    Ikonen, T.
    Bhattacharya, A.
    Ala-Nissila, T.
    Sung, W.
    JOURNAL OF CHEMICAL PHYSICS, 2012, 137 (08):
  • [9] Dual Scale Roughness Driven Perfectly Hydrophobic Surfaces Prepared by Electrospraying a Polymer in Good Solvent-Poor Solvent Systems
    Simsek, Eren
    Acatay, Kazim
    Menceloglu, Yusuf Z.
    LANGMUIR, 2012, 28 (40) : 14192 - 14201
  • [10] STUDY OF THE SURFACE-TENSION OF POLYMER-SOLUTIONS - THEORY AND EXPERIMENTS .1. GOOD SOLVENT CONDITIONS
    OBER, R
    PAZ, L
    TAUPIN, C
    PINCUS, P
    BOILEAU, S
    MACROMOLECULES, 1983, 16 (01) : 50 - 55