Screening and surveillance in hereditary gastrointestinal cancers: Recommendations from the European Society of Digestive Oncology (ESDO) expert discussion at the 20th European Society for Medical Oncology (ESMO)/World Congress on Gastrointestinal Cancer, Barcelona, June 2018

被引:54
|
作者
Vangala, Deepak B. [1 ]
Cauchin, Estelle [2 ]
Balmana, Judith [3 ,4 ]
Wyrwicz, Lucian [5 ,6 ]
van Cutsem, Eric [7 ,8 ]
Guller, Ulrich [9 ]
Castells, Antoni [10 ]
Carneiro, Fatima [11 ,12 ]
Hammel, Pascal [13 ]
Ducreux, Michel [14 ,15 ]
van Laethem, Jean-Luc [16 ]
Matysiak-Budnik, Tamara [2 ]
Schmiegel, Wolff [1 ]
机构
[1] Ruhr Univ Bochum, Knappschaftskrankenhaus, Dept Internal Med, Bochum, Germany
[2] Nantes Univ Hosp, Inst Malad Appareil Digestif, Hepatogastroenterol & Digest Oncol, Nantes, France
[3] Vall DHebron Univ Hosp, Barcelona, Spain
[4] Inst Oncol, Barcelona, Spain
[5] Maria Sklodowska Curie Mem Canc Ctr, Warsaw, Poland
[6] Inst Oncol, Warsaw, Poland
[7] Univ Hosp, Digest Oncol, Leuven, Belgium
[8] Katholieke Univ Leuven, Leuven, Belgium
[9] Kantonsspital St Gallen, Div Med Oncol & Hematol, St Gallen, Switzerland
[10] Univ Barcelona, Hosp Clin, IDIBAPS, Gastroenterol Dept,CIBEREHD, Barcelona, Catalonia, Spain
[11] Univ Porto FMUP, Fac Med, CHSJ, Porto, Portugal
[12] Ipatimup i3S, Porto, Portugal
[13] Univ Paris VII Denis Diderot, Hop Beaujon, Dept Digest Oncol, Clichy, France
[14] Gustave Roussy, Dept Med Oncol, Villejuif, France
[15] Univ Paris Saclay, St Aubain, France
[16] Univ Libre Bruxelles, Hop Erasme, Dept Gastroenterol & Digest Oncol, Brussels, Belgium
关键词
Hereditary GI cancer; Surveillance; Screening; Hereditary diffuse gastric cancer; Lynch syndrome; Polyposis; Familial pancreatic cancer; DIFFUSE GASTRIC-CANCER; COLORECTAL-CANCER; LYNCH-SYNDROME; PANCREATIC-CANCER; GERMLINE MUTATIONS; HIGH PROPORTION; RISK-FACTORS; FAMILIES; GUIDELINES; MANAGEMENT;
D O I
10.1016/j.ejca.2018.09.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Patients with hereditary gastrointestinal (GI) cancers represent a substantial fraction of the overall affected population. Although awareness for hereditary GI cancer syndromes is on the rise, identification of patients and measures of surveillance are often unclear in everyday clinical routine. Therefore, the European Society of Digestive Oncology expert discussion 2018 at the World Congress on Gastrointestinal Cancer focussed on screening and surveillance of hereditary colorectal, gastric and pancreatic cancers. An international panel of experts and opinion leaders developed the here presented recommendations based on published evidence and on profound clinical expertise to facilitate clinical routine in identification and caretaking of patients with familial GI cancers. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:91 / 103
页数:13
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