Coherent spontaneous activity accounts for trial-to-trial variability in human evoked brain responses

被引：531
作者：
Fox, MD [1 ]
Snyder, AZ
Zacks, JM
Raichle, ME
机构：
[1] Washington Univ, Dept Radiol, St Louis, MO 63110 USA
[2] Washington Univ, Dept Neurol, St Louis, MO 63110 USA
[3] Washington Univ, Dept Psychol, St Louis, MO 63110 USA
[4] Washington Univ, Dept Anat & Neurobiol, St Louis, MO 63110 USA
[5] Washington Univ, Dept Biomed Engn, St Louis, MO 63110 USA
来源：
NATURE NEUROSCIENCE | 2006年 / 9卷 / 01期
关键词：
D O I：
10.1038/nn1616
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Trial-to-trial variability in the blood oxygen level-dependent (BOLD) response of functional magnetic resonance imaging has been shown to be relevant to human perception and behavior, but the sources of this variability remain unknown. We demonstrate that coherent spontaneous fluctuations in human brain activity account for a significant fraction of the variability in measured event-related BOLD responses and that spontaneous and task-related activity are linearly superimposed in the human brain.
引用
收藏
页码：23 / 25
页数：3
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