Near-infrared spectroscopic photoacoustic microscopy using a multi-color fiber laser source

被引：23

作者：

Buma, Takashi ^{[1
,2
]}

Wilkinson, Benjamin C. ^{[2
]}

Sheehan, Timothy C. ^{[2
]}

机构：

[1] Union Coll, Dept Elect & Comp Engn, Schenectady, NY 12308 USA

[2] Union Coll, Bioengn Program, Schenectady, NY 12308 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2015年 / 6卷 / 08期

基金：

美国国家科学基金会;

关键词：

RESOLUTION; SUPERCONTINUUM; SPECTRUM; TISSUE;

D O I：

10.1364/BOE.6.002819

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrate a simple multi-wavelength optical source suitable for spectroscopic optical resolution photoacoustic microscopy (OR-PAM) of lipid-rich tissue. 1064 nm laser pulses are converted to multiple wavelengths beyond 1300 nm via nonlinear optical propagation in a birefringent optical fiber. OR-PAM experiments with lipid phantoms clearly show the expected absorption peak near 1210 nm. We believe this simple multi-color technique is a promising cost-effective approach to spectroscopic OR-PAM of lipid-rich tissue. (C) 2015 Optical Society of America

引用

页码：2819 / 2829

页数：11

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