Advances in Lignans with anti-HIV properties

被引：0
|
作者：
Yang, Y [1 ]
Zhang, CL
Wang, Z
Pan, XF
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Dept Chem, Lanzhou 730000, Peoples R China
[2] Dupont Merck Pharmaceut Co, Res & Dev Chambers Works, Deepwater, NJ 08023 USA
来源：
PROGRESS IN CHEMISTRY | 2003年 / 15卷 / 04期
关键词：
lignans; HIV; enzyme inhibitor;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Lignans exhibit various biological activities, such as antitumor, antihepatotoxic, blood plate activating factor inhibiting and antioxidant activity. However, its anti-HIV property has not been reported until 1990. As antiviral agents, lignans were isolated from plants, which are safe to human cells and have the probability to be the medicines of AIDS treatments. The research on lignans with anti-HIV properties in recent years is reviewed in this paper.
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页码：327 / 331
页数：5
相关论文
共 28 条
  • [1] DIFFERENTIAL INHIBITION OF REVERSE-TRANSCRIPTASE AND CELLULAR DNA POLYMERASE-ALPHA ACTIVITIES BY LIGNANS ISOLATED FROM CHINESE HERBS, PHYLLANTHUS-MYRTIFOLIUS MOON, AND TANNINS FROM LONICERA-JAPONICA THUNB AND CASTANOPSIS-HYSTRIX
    CHANG, CW
    LIN, MT
    LEE, SS
    LIU, KCSC
    HSU, FL
    LIN, JY
    [J]. ANTIVIRAL RESEARCH, 1995, 27 (04) : 367 - 374
  • [2] Anti-AIDS agents .26. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues
    Chen, DF
    Zhang, SX
    Xie, L
    Xie, JX
    Chen, K
    Kashiwada, Y
    Zhou, BN
    Wang, P
    Cosentino, LM
    Lee, KH
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 1997, 5 (08) : 1715 - 1723
  • [3] Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior
    Chen, DF
    Zhang, SX
    Chen, K
    Zhou, BN
    Wang, P
    Cosentino, LM
    Lee, KH
    [J]. JOURNAL OF NATURAL PRODUCTS, 1996, 59 (11): : 1066 - 1068
  • [4] Antiviral activities of methylated nordihydroguaiaretic acids.: 2.: Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA
    Chen, HS
    Teng, L
    Li, JN
    Park, R
    Mold, DE
    Gnabre, J
    Hwu, JR
    Tseng, WN
    Huang, RCC
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (16) : 3001 - 3007
  • [5] Lignans from the rhizomes of Coptis japonica differentially act as anti-inflammatory principles
    Cho, JY
    Kim, AR
    Park, MH
    [J]. PLANTA MEDICA, 2001, 67 (04) : 312 - 316
  • [6] CRAIGO J, 2000, RES, V47, P367
  • [7] Assessment of the anti-HIV activity of a pine cone isolate
    Eberhardt, TL
    Young, RA
    [J]. PLANTA MEDICA, 1996, 62 (01) : 63 - 65
  • [8] EICH E, 1990, Planta Medica, V56, P506, DOI 10.1055/s-2006-961045
  • [9] (-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase
    Eich, E
    Pertz, H
    Kaloga, M
    Schulz, J
    Fesen, MR
    Mazumder, A
    Pommier, Y
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (01) : 86 - 95
  • [10] ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) ACTIVITIES OF HALOGENATED GOMISIN-J DERIVATIVES, NEW NONNUCLEOSIDE INHIBITORS OF HIV TYPE-1 REVERSE-TRANSCRIPTASE
    FUJIHASHI, T
    HARA, H
    SAKATA, T
    MORI, K
    HIGUCHI, H
    TANAKA, A
    KAJI, H
    KAJI, A
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (09) : 2000 - 2007
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