EMHP: an accurate automated hole masking algorithm for single-particle cryo-EM image processing

被引：18
|
作者：
Berndsen, Zachary [1 ]
Bowman, Charles [1 ]
Jang, Haerin [1 ]
Ward, Andrew B. [1 ]
机构：
[1] Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA
来源：
BIOINFORMATICS | 2017年 / 33卷 / 23期
关键词：
D O I：
10.1093/bioinformatics/btx500
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A Summary: The Electron Microscopy Hole Punch (EMHP) is a streamlined suite of tools for quick assessment, sorting and hole masking of electron micrographs. With recent advances in single-particle electron cryo-microscopy (cryo-EM) data processing allowing for the rapid determination of protein structures using a smaller computational footprint, we saw the need for a fast and simple tool for data pre-processing that could run independent of existing high-performance computing (HPC) infrastructures. EMHP provides a data preprocessing platform in a small package that requires minimal python dependencies to function.
引用
收藏
页码：3824 / 3826
页数：3
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