Micro-computed tomography for small animal imaging: Technological details

被引:41
|
作者
Li, Hao [1 ]
Zhang, Hui [1 ]
Tang, Zhiwei [1 ]
Hu, Guangshu [1 ]
机构
[1] Tsinghua Univ, Dept Biomed Engn, Beijing 100084, Peoples R China
关键词
micro-computed tomography; small animal; X-ray;
D O I
10.1016/j.pnsc.2008.01.002
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The high-resolution micro-computed tomography (micro-CT) system has now become an important tool for biological research. The micro-CT system enables a non-invasive inspection to screen anatomical changes in small animals. The promising advantages include high-spatial resolution, high sensitivity to bone and lung, short scan time and cost-effectiveness. The dose received by the small animal might be a critical concern in the research. In this article, the choice of the components, fundamental physical problems, the image reconstruction algorithm and the representative applications of micro-CT are summarized. Some results from our research group are also presented to show high-resolution images obtained by the micro-CT system. (c) 2008 National Natural Science Foundation of China and Chinese Academy of Sciences. Published by Elsevier Limited and Science in China Press. All rights reserved.
引用
收藏
页码:513 / 521
页数:9
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