Wilms Tumor After Orthotopic Liver Transplant in a Patient With Alagille Syndrome

被引：0

作者：

Carlos, Evan C.

Ajay, Divya

Muniz-Alers, Saisha

Wechsler, Daniel S.

Sushama, Deepak Vikraman

Rice, Henry E.

Madden, John

Routh, Jonathan C.

机构：

[1] Duke Univ, Med Ctr, Dept Surg, Div Urol, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Dept Pediat, Div Hematol Oncol, Durham, NC 27710 USA

[3] Emory Univ, Childrens Healthcare Atlanta, Aflac Canc & Blood Disorders Ctr, Durham, NC USA

[4] Duke Univ, Med Ctr, Dept Surg, Div Transplant Surg, Durham, NC 27710 USA

[5] Duke Univ, Med Ctr, Dept Surg, Div Pediat Gen Surg, Durham, NC 27710 USA

[6] Duke Univ, Med Ctr, Dept Pathol, Durham, NC 27710 USA

来源：

UROLOGY | 2018年 / 121卷

关键词：

D O I：

10.1016/j.urology.2018.05.020

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of Wilms Tumor in a patient with Alagille syndrome 10 months after liver transplant. We explore a suggested genetic connection between these 2 diseases. In children with Wilms Tumor, we propose a pathoembryologic explanation for not just the tumor, but also for the cause of associated benign ureteral and renal parenchymal aberrancies that are commonly seen in the Alagille population. We also discuss the diagnostic and therapeutic challenges that can arise in a liver transplant patient with Alagille syndrome who subsequently develops a renal mass. (C)2018 Elsevier Inc.

引用

页码：171 / 174

页数：4

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