A decade of yeast surface display technology: Where are we now?

被引：1
|
作者：
Pepper, Lauren R. [2 ]
Cho, Yong Ku [1 ]
Boder, Eric T. [2 ,3 ]
Shusta, Eric V. [1 ]
机构：
[1] Univ Wisconsin, Dept Chem & Biol Chem, Madison, WI 53706 USA
[2] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[3] Univ Tennessee, Dept Chem & Biomol Engn, Knoxville, TN 37996 USA
来源：
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING | 2008年 / 11卷 / 02期
关键词：
yeast surface display; protein engineering; library screening;
D O I：
暂无
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Yeast surface display has become an increasingly popular tool for protein engineering and library screening applications. Recent advances have greatly expanded the capability of yeast surface display, and are highlighted by cell-based selections, epitope mapping, cDNA library screening, and cell adhesion engineering. In this review, we discuss the state-of-the-art yeast display methodologies and the rapidly expanding set of applications afforded by this technology.
引用
收藏
页码：127 / 134
页数：8
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