Recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme produced in pichia pastoris as an alternative for Morquio syndrome type A ERT

被引:1
|
作者
Rodriguez-Lopez, Alexander [1 ]
Pimentel-Vera, Luisa N. [1 ]
Espejo-Mojica, Angela J. [1 ]
Hidalgo, Oscar A. [1 ]
Tomatsu, Shunji [2 ]
Almeciga-Diaz, Carlos J. [1 ]
机构
[1] Pontificia Univ Javeriana, Bogota, Colombia
[2] Nemours Alfred I duPont Hosp Children, Wilmington, DE USA
关键词
D O I
10.1016/j.ymgme.2017.12.335
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
326
引用
收藏
页码:S123 / S123
页数:1
相关论文
共 50 条
  • [1] Recombinant human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in the methylotrophic yeast Pichia pastoris
    Alexander Rodríguez-López
    Carlos J. Alméciga-Díaz
    Jhonnathan Sánchez
    Jefferson Moreno
    Laura Beltran
    Dennis Díaz
    Andrea Pardo
    Aura María Ramírez
    Angela J. Espejo-Mojica
    Luisa Pimentel
    Luis A. Barrera
    Scientific Reports, 6
  • [2] Recombinant human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in the methylotrophic yeast Pichia pastoris
    Rodriguez-Lopez, Alexander
    Almeciga-Diaz, Carlos J.
    Sanchez, Jhonnathan
    Moreno, Jefferson
    Beltran, Laura
    Diaz, Dennis
    Pardo, Andrea
    Maria Ramirez, Aura
    Espejo-Mojica, Angela J.
    Pimentel, Luisa
    Barrera, Luis A.
    SCIENTIFIC REPORTS, 2016, 6
  • [3] Cell uptake evaluation of human recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in Pichia pastoris
    Rodriguez-Lopez, Alexander
    Cardona, Carolina
    Pimentel, Natalia
    Espejo-Mojica, Angela J.
    Almeciga-Diaz, Carlos J.
    MOLECULAR GENETICS AND METABOLISM, 2017, 120 (1-2) : S116 - S116
  • [4] Production of recombinant human N-acetylgalactosamine-6-sulfate sulfatase enzyme in Pichia pastoris
    Rodriguez, Alexander
    Moreno, Jefferson
    Sanchez, Jhonnathan
    Diaz, Dennis
    Beltran, Laura
    Espejo, Angela
    Almeciga, Carlos
    Barrera, Luis
    MOLECULAR GENETICS AND METABOLISM, 2013, 108 (02) : S79 - S80
  • [5] Production of an active recombinant human N-acetylgalactosamine-6-sulfate sulfatase enzyme in Pichia pastoris
    Almeciga, Carlos J.
    Rodriguez-Lopez, Alexander
    Sanchez, Jhonnathan
    Moreno, Jefferson
    Diaz, Dennis
    Beltran, Laura M.
    Espejo, Angela J.
    Ruiz, Freddy O.
    Barrera Pontificia, Luis A.
    MOLECULAR GENETICS AND METABOLISM, 2014, 111 (02) : S19 - S19
  • [6] Characterization of Human Recombinant N-Acetylgalactosamine-6-Sulfate Sulfatase Produced in Pichia pastoris as Potential Enzyme for Mucopolysaccharidosis IVA Treatment
    Rodriguez-Lopez, Alexander
    Pimentel-Vera, Luisa N.
    Espejo-Mojica, Angela J.
    Van Hecke, Annelies
    Tiels, Petra
    Tomatsu, Shunji
    Callewaert, Nico
    Almeciga-Diaz, Carlos J.
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 108 (08) : 2534 - 2541
  • [7] Human recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in a glycoengineered Escherichia coli strain
    Almeciga-Diaz, Carlos J.
    Pimentel-Vera, Luisa N.
    Rodriguez-Lopez, Alexander
    Espejo-Mojica, Angela
    Ramirez, Aura M.
    Cardona, Carolina
    Reyes, Luis H.
    DeLisa, Matthew P.
    Sanchez, Oscar F.
    MOLECULAR GENETICS AND METABOLISM, 2017, 120 (1-2) : S20 - S20
  • [8] Fifteen polymorphisms in the N-acetylgalactosamine-6-sulfate sulfatase (GALNS) gene: Diagnostic implications in Morquio disease
    Tomatsu, SJ
    Fukuda, S
    Cooper, A
    Wraith, JE
    Yamagishi, A
    Kato, Z
    Yamada, N
    Isogai, K
    Sukegawa, K
    Suzuki, Y
    Shimozawa, N
    Kondo, N
    Orii, T
    HUMAN MUTATION, 1998, : S42 - S46
  • [9] N-ACETYLGALACTOSAMINE-6-SULFATE SULFATASE IN MAN - ABSENCE OF ENZYME IN MORQUIO DISEASE
    SINGH, J
    DIFERRANTE, N
    NIEBES, P
    TAVELLA, D
    JOURNAL OF CLINICAL INVESTIGATION, 1976, 57 (04): : 1036 - 1040
  • [10] Characterization of a recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in E. coli for enzyme replacement therapy of Morquio A disease
    Mosquera, Angela
    Rodriguez, Alexander
    Soto, Carlos
    Leonardi, Felice
    Espejo, Angela
    Sanchez, Oscar F.
    Almeciga-Diaz, Carlos J.
    Barrera, Luis A.
    PROCESS BIOCHEMISTRY, 2012, 47 (12) : 2097 - 2102