Molecular processes and structural alterations in laser reshaping of cartilage

被引:19
|
作者
Ignatieva, N.
Zakharkina, O.
Leroy, G.
Sobol, E.
Vorobieva, N.
Mordon, S.
机构
[1] Russian Acad Sci, Inst Laser & Informat Technol, R-142090 Troitsk, Russia
[2] Moscow MV Lomonosov State Univ, Dept Chem, R-11992 Moscow, Russia
[3] Lille Univ Hosp, Dept Odontol, IFR 114, IMPRT, Lille, France
[4] Lille Univ Hosp, INSERM, IFR 114, Lille, France
关键词
microscopy; Raman spectroscopy; laser irradiation; cartilage;
D O I
10.1002/lapl.200710042
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
The effects of non-destructive laser irradiation on the structure and molecular processes in cartilage were studied using Raman microscopy, differential scanning calorimetry and biochemical analysis. A structural reorganization of the irradiated tissue similar to poliginization in polycrystalline solids was observed for the first time in a cartilage matrix. The difference in the Raman spectra of the irradiated and control samples was interpreted in term of a conformational. alteration of glycosaminoglycan macromolecules in the reshaping mode. Laser induced modification of collagen macromolecules was not revealed by Raman spectroscopy. Thermal and biochemical analysis confirmed a preservation of triple helix for laser settings used for laser-induced stress relaxation and reshaping of cartilage.
引用
收藏
页码:749 / 753
页数:5
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