Multicyclic dose-intensive chemotherapy supported by autologous blood progenitor cell transplantation for relapsed small cell lung cancer

被引：0

作者：

Fujimoto, N ^{[1
]}

Ueoka, H ^{[1
]}

Kiura, K ^{[1
]}

Tabata, M ^{[1
]}

Bessho, A ^{[1
]}

Takata, I ^{[1
]}

Sunami, K ^{[1
]}

Hiramatsu, Y ^{[1
]}

Ikeda, K ^{[1
]}

Tanimoto, M ^{[1
]}

Harada, M ^{[1
]}

机构：

[1] Okayama Univ, Sch Med, Dept Internal Med 2, Okayama 7008558, Japan

来源：

ANTICANCER RESEARCH | 2003年 / 23卷 / 5B期

关键词：

dose-intensive chemotherapy; autologous blood progenitor cell transplantation (ABPCT); small cell lung cancer; second-line chemotherapy;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report two cases with small cell lung cancer (SCLC) receiving multicyclic dose-intensified chemotherapy (DI-CT) supported by autologous blood progenitor cell transplantation (ABPCT). Both cases were initially treated with cisplatin (CDDP), etoposide (ETP) and concurrent thoracic irradiation, however they had recurrent disease within a year. After receiving conventional chemotherapy, they underwent multicyclic DI-CT consisting of CDDP, ETP and ifosfamide supported by G-CSF and ABPCT. Definite regression of the tumors was observed. Severe neutropenia and thrombocytopenia were encountered but they were reversible and no life-threatening complications were experienced. These results suggest the feasibility and effectiveness of multicyclic DI-CT and the usefulness of ABPCT as a treatment option for relapsed SCLC.

引用

页码：4229 / 4232

页数：4

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