New and sensitive assay for determining Pseudomonas aeruginosa metallo-beta-lactamase resistance to imipenem

被引：6
|
作者：
Tan, Jingyuan [2 ]
Pitout, Johann D. D. [3 ,4 ,5 ]
Guttman, David S. [1 ]
机构：
[1] Univ Toronto, Ctr Anal Genome Evolut & Funct, Toronto, ON M5S 3B2, Canada
[2] Univ Toronto, Dept Cell & Syst Biol, Toronto, ON, Canada
[3] Univ Calgary, Dept Pathol & Lab Med, Calgary, AB, Canada
[4] Univ Calgary, Dept Microbiol & Infect Dis, Calgary, AB, Canada
[5] Univ Calgary, Dept Microbiol, Calgary Lab Serv, Calgary, AB, Canada
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 05期
关键词：
D O I：
10.1128/JCM.02175-07
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We present an imipenem lysate metallo-beta-lactamase (MBL) functional assay. This assay eliminates false-positive results due to the bactericidal effects of EDTA, can be performed with inexpensive reagents available in most laboratories, and is as accurate as the MBL Etest. It is appropriate for both high-accuracy screens and laboratories in developing countries with limited resources.
引用
收藏
页码：1870 / 1872
页数：3
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