Control of gene transcription by Mediator in chromatin

被引：11
|
作者：
Ries, David [1 ]
Meisterernst, Michael [1 ]
机构：
[1] Univ Munster, Inst Mol Tumor Biol IMTB, D-48149 Munster, Germany
来源：
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2011年 / 22卷 / 07期
关键词：
Kinase; Transcription; Chromatin; PC2; Regulation; RNA-POLYMERASE-II; THYROID-HORMONE RECEPTOR; CARBOXY-TERMINAL DOMAIN; PROLIFERATOR-ACTIVATED RECEPTOR; COACTIVATOR COMPLEX; IN-VIVO; NUCLEAR RECEPTORS; DROSOPHILA-MELANOGASTER; DEPENDENT TRANSCRIPTION; FUNCTIONAL INTERACTIONS;
D O I：
10.1016/j.semcdb.2011.08.004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The Mediator complex serves as an adaptor for regulatory factors, recruits and controls RNA polymerase II promotes preinitiation complex formation and functions post initiation. There is increasing evidence for further coordinating roles of the Mediator complex in chromatin. Here we summarize interactions with regulatory, general and accessory factors that function in transcription and chromatin. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：735 / 740
页数：6
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