SYNTHESIS AND PHARMACOLOGICAL SCREENING OF NEW BENZIMIDAZOLE DERIVATIVES

被引:0
|
作者
Harika, M. Sai [1 ]
Bhargavi, S. [1 ]
Renukadevi, V. [1 ]
Karishma, S. [1 ]
Abbinaya, L. [1 ]
Ramya, L. [1 ]
Subhhashini, P. [1 ]
机构
[1] Creat Educ Soci Coll Pharm, Dept Pharmaceut Chem, Kurnool, Andhra Pradesh, India
关键词
Antihelmentic; Antitubercular; Benzimidazole; Fourier transform infrared; H-1 Nuclear magnetic resonance;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Six new 2-substituted benzimidazoles (C1-C6) were synthesized by condensation of o-phenylendediamine with different acids (aliphatic, aromatic, fatty acids, and amino acids). The antihelmintic and antitubercular activities of the compounds were also evaluated.
引用
收藏
页码:217 / 221
页数:5
相关论文
共 50 条
  • [1] Synthesis, characterization and pharmacological screening of novel benzimidazole derivatives
    Shaharyar, Mohammad
    Mazumder, Avijit
    Salahuddin
    Garg, Ruchika
    Pandey, Rishabh D.
    ARABIAN JOURNAL OF CHEMISTRY, 2016, 9 : S342 - S347
  • [2] Synthesis and pharmacological screening of derivatives of benzimidazole linked with quinoline and tetrazole
    Uttarwar, Rajshri B.
    Nawale, Rajesh B.
    Shamkuwar, Prashant B.
    Journal of Chemical and Pharmaceutical Research, 2013, 5 (04) : 41 - 46
  • [3] Design, Synthesis, Pharmacological Screening and Molecular Docking Study of New Substituted Benzimidazole Derivatives
    Nalini, C. N.
    Prabakaran, A.
    Jayasree, R.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2023, 57 (01) : 51 - 59
  • [4] Design, Synthesis, Pharmacological Screening and Molecular Docking Study of New Substituted Benzimidazole Derivatives
    C. N. Nalini
    A. Prabakaran
    R. Jayasree
    Pharmaceutical Chemistry Journal, 2023, 57 : 51 - 59
  • [5] SYNTHESIS AND BIOLOGICAL SCREENING OF BENZIMIDAZOLE DERIVATIVES
    Shukla, Ankur
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (03): : 922 - 927
  • [6] SYNTHESIS AND PHARMACOLOGICAL SCREENING OF NEW PHENYLPIPERAZINEPROPANE DERIVATIVES AND THEIR ENANTIOMERS
    GIANI, R
    MARINONE, E
    MELILLO, G
    BORSA, M
    TONON, GC
    ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 1988, 38-2 (08): : 1139 - 1141
  • [7] SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF SOME BENZIMIDAZOLE DERIVATIVES .8. BENZIMIDAZOLE DERIVATIVES OF UREA
    MUKHINA, NA
    SHKRABOVA, LV
    ROMANOVA, TV
    PECHENINA, VM
    KAZAKOVA, VP
    PASHINSKY, VG
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1979, 13 (10): : 39 - 44
  • [8] A Review on the Green Synthesis of Benzimidazole Derivatives and Their Pharmacological Activities
    Nardi, Monica
    Cano, Natividad Carolina Herrera
    Simeonov, Svilen
    Bence, Renata
    Kurutos, Atanas
    Scarpelli, Rosa
    Wunderlin, Daniel
    Procopio, Antonio
    CATALYSTS, 2023, 13 (02)
  • [9] Applying Nanotechnology in the Synthesis of Benzimidazole Derivatives: A Pharmacological Approach
    El-Sayed, Ahmed A.
    Abu-Bakr, Sherifa M.
    Swelam, Samira A.
    Khaireldin, Nahid Y.
    Shoueir, Kamel R.
    Khalil, Ahmed M.
    BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2022, 12 (01): : 992 - 1005
  • [10] Synthesis, Structure Elucidation, and Pharmacological Study of New Hydrazinylidene Derivatives Using Benzimidazole as a Scaffold
    K. R. Al-Jorani
    A. J. K. Atia
    R. I. Al-Bayti
    Russian Journal of Bioorganic Chemistry, 2021, 47 : 945 - 953