A single stranded fluorescent peptide probe for targeting collagen in connective tissues

被引：21

作者：

Cai, Xiangdong ^{[1
]}

Liu, Zhao ^{[1
]}

Zhao, Sha ^{[1
]}

Song, Chen ^{[1
]}

Dong, Shouliang ^{[2
]}

Xiao, Jianxi ^{[1
]}

机构：

[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Gansu, Peoples R China

[2] Lanzhou Univ, Inst Biochem & Mol Biol, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 87期

基金：

中国国家自然科学基金;

关键词：

MIMETIC PEPTIDES; CANCER; ANGIOGENESIS; CARTILAGE; OVARIAN; IV;

D O I：

10.1039/c7cc06056d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We herein report the construction of a novel single stranded fluorescent collagen mimetic peptide by introducing a bulky FAM dye in the central region rather than the N terminus. Without the need for any prior thermal or ultraviolet treatment, the peptide probe can be conveniently applied to specifically target collagen in connective tissues for fluorescence imaging.

引用

页码：11905 / 11908

页数：4

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