Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak

被引:8
|
作者
Hu, Liming [1 ]
Calucho, Enric [1 ]
Fuentes-Chust, Celia [1 ]
Parolo, Claudio [1 ,2 ]
Idili, Andrea [1 ]
Alvarez-Diduk, Ruslan [1 ]
Rivas, Lourdes [1 ]
Merkoci, Arben [1 ,3 ]
机构
[1] Catalan Inst Nanosci & Nanotechnol ICN2, BIST, CSIC, Nanobioelect & Biosensors Grp, Campus UAB, Barcelona 08193, Spain
[2] Univ Barcelona, Hosp Clin, Barcelona Ctr Int Hlth Res CRESIB, ISGlobal,Dept Int Hlth, Barcelona, Spain
[3] Inst Catalana Recerca & Estudis Avancats, ICREA, Barcelona, Spain
基金
欧洲研究理事会; 欧盟地平线“2020”;
关键词
ANTIBODIES;
D O I
10.1039/d2lc00486k
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This manuscript aims at raising the attention of the scientific community to the need for better characterised bioreceptors for fast development of point-of-care diagnostic devices able to support mass frequency testing. Particularly, we present the difficulties encountered in finding suitable antibodies for the development of a lateral flow assay for detecting the nucleoprotein of SARS-CoV-2.
引用
收藏
页码:2938 / 2943
页数:6
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