Structure of the rat gene encoding the multifunctional acyl-CoA-binding protein: Conservation of intron 1 sequences in rodents and man

被引：2
|
作者：
Kroll, JB
Nohr, J
Gregersen, N
Kristiansen, K
Mandrup, S
机构：
[1] ODENSE UNIV,DEPT MOL BIOL,DK-5230 ODENSE M,DENMARK
[2] AARHUS UNIV,AARHUS UNIV HOSP,CTR MED MOL BIOL,DK-8000 AARHUS C,DENMARK
来源：
GENE | 1996年 / 173卷 / 02期
关键词：
alternative splicing; CpG islands; DNA sequencing; repetitive elements;
D O I：
10.1016/0378-1119(96)00214-4
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The entire gene encoding the rat acyl-CoA-binding protein (ACBP), and intron 1 of the mouse and human ACBP genes were sequenced and analyzed. A CpG island has been maintained in human ACBP which, in contrast to the rodent ACBP genes, is subject to alternative splicing. Analysis of the rat intron 2 and 3 sequences identified a number of potential alternative splice donor and splice acceptor sites. However, RNase protection analysis revealed no alternatively spliced transcripts in RNA from various rat tissues. Several repetitive elements belonging to the ID, B1 and B2 families are present in introns 2 and 3.
引用
收藏
页码：239 / 240
页数：2
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