Synthesis of Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x ≤ 0.25) nanofibers by using electrospinning technique induce anti-cancer and anti-bacterial activities

被引:19
|
作者
Alahmari, F. [1 ]
Rehman, S. [2 ]
Almessiere, M. [3 ]
Khan, F. A. [4 ]
Slimani, Y. [3 ]
Baykal, A. [1 ]
机构
[1] Imam Abdulrahman Bin Faisal Univ, Dept Nanomed, Dammam, Saudi Arabia
[2] Imam Abdulrahman Bin Faisal Univ, Dept Epidem Dis Res, Dammam, Saudi Arabia
[3] Imam Abdulrahman Bin Faisal Univ, Dept Biophys, Dammam, Saudi Arabia
[4] Imam Abdulrahman Bin Faisal Univ, IRMC, Dept Stem Cell Res, POB 1982, Dammam 31441, Saudi Arabia
来源
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 2021年 / 39卷 / 09期
关键词
Spinel ferrites nanoparticles; electrospinning technique; XRD; TEM; anti-cancer agent; anti-bacterial agent; NANOPARTICLES; NI; CU;
D O I
10.1080/07391102.2020.1761880
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Here we report the electrospinning synthesis of Cd-substituted Ni-Co ferrite Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x <= 0.25) nanofiber (NFs) with a very low concentration of Nd as a dopant. The structure and surface morphology of the Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x <= 0.25) NFs were analyzed by X-ray powder pattern (XRD), transmission and scanning electron microscopes (TEM) along with Energy-dispersive X-ray (EDX). We have examined the biological applications of the Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x <= 0.25) NFs on both cancerous cells and bacterial cells. We have found that Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x <= 0.25) NFs produced inhibitory action on the human colorectal carcinoma cells (HEK-293) and also showed inhibitory action on the bacterial strains (S. aureus and E. coli) respectively. Finally, this is the first report on the synthesis of Cd- substituted Co-Ni ferrite nanofibers using electrospinning technique exhibiting anti-cancer and anti-bacterial activities. Communicated by Ramaswamy H. Sarma
引用
收藏
页码:3186 / 3193
页数:8
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