Excessive daytime sleepiness and narcolepsy - An approach to investigation and management

被引:17
|
作者
Morrison, Ian [1 ]
Riha, Renata L. [2 ]
机构
[1] Ninewells Hosp, Dept Neurol, Dundee DD1 9SY, Scotland
[2] Royal Infirm Edinburgh NHS Trust, Dept Sleep Med, Edinburgh EH16 4SA, Midlothian, Scotland
关键词
Narcolepsy review; Excessive daytime sleepiness; Hypersomnia; Investigation of sleepiness; Treatment of narcolepsy and cataplexy; GAMMA-HYDROXYBUTYRIC ACID; BODY-MASS INDEX; INTRAVENOUS IMMUNOGLOBULINS; INDUCED WAKEFULNESS; ENERGY HOMEOSTASIS; CLINICAL-FEATURES; HYPOCRETIN OREXIN; BEHAVIOR-DISORDER; CANINE NARCOLEPSY; ICSD-2; CRITERIA;
D O I
10.1016/j.ejim.2011.09.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Excessive daytime sleepiness is a common presentation to physicians both in general practice and hospital settings. In this review, we provide an update on the latest theories on the pathogenesis of the condition, and discuss the approach to investigation of the sleepy patient, with particular reference to narcolepsy. Recommended therapy is reviewed for both narcolepsy and cataplexy, to provide physicians with an important reference on the investigation and management of these troubling conditions. (C) 2011 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:110 / 117
页数:8
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