How low can you go? Achieved blood pressure and cardiovascular outcomes

被引:2
|
作者
Wyatt, Christina M. [1 ]
Cheung, Alfred K. [2 ,3 ,4 ]
机构
[1] Icahn Sch Med Mt Sinai, Div Nephrol, Dept Med, New York, NY 10029 USA
[2] Univ Utah, Div Nephrol & Hypertens, Salt Lake City, UT USA
[3] Vet Affairs Salt Lake City Healthcare Syst, Med Serv, Salt Lake City, UT USA
[4] Cent South Univ, Xiangya Hosp 2, Dept Nephrol, Changsha, Hunan, Peoples R China
关键词
cardiovascular disease; congestive heart failure;
D O I
10.1016/j.kint.2017.07.002
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The benefits of controlling blood pressure to levels < 140/90 mm Hg are well established, but the risks and benefits of further reductions in blood pressure are less clear. A recent observational study using pooled data from 2 large randomized trials of renin-angiotensin system blockers suggested no added benefit and some increased risk of cardiovascular events with achieved blood pressures < 120 mm Hg systolic or 70 mm Hg diastolic. Caveats of observational studies notwithstanding, these results add to the ongoing controversy over the optimal blood pressure target for high-risk individuals.
引用
收藏
页码:536 / +
页数:5
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