High expressed IL-12 beta 2 receptor (IL-12b2R) is associated with Th1-type response in Experimental Autoimmune Uveitis (EAU)

被引：0
|
作者：
Sun, B
Wu, YD
Zhang, CP
机构：
[1] Shanghai Inst Cell Biol, Lab Mol Immunol, Shanghai 200031, Peoples R China
[2] Shanghai Med Univ, Shanghai 200032, Peoples R China
来源：
FASEB JOURNAL | 2001年 / 15卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A1215 / A1215
页数：1
相关论文
共 50 条
  • [1] Intranasal IL-12 delivery enhances Th2-type while oral IL-12 redirects Th2- to Th1-type responses
    Marinaro, M
    Boyaka, PN
    Jackson, RJ
    Finkelman, FD
    Kiyono, H
    McGhee, JR
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (01) : 142 - 142
  • [2] Characterization of IL-12 receptor beta 1 chain (IL-12R beta 1)-deficient mice - IL-12R beta 1 is an essential component of the functional mouse IL-12 receptor
    Wu, CY
    Ferrante, J
    Gately, MK
    Magram, J
    JOURNAL OF IMMUNOLOGY, 1997, 159 (04): : 1658 - 1665
  • [3] IFN-γ up-regulation of IL-12 beta 2 receptor is associated with experimental autoimmune uveitis susceptible B10.A mice, but not in EAU resistant BALB/c mice
    Wu, YD
    Lin, Y
    Hou, WQ
    Wang, YP
    Sun, B
    JOURNAL OF NEUROIMMUNOLOGY, 2003, 137 (1-2) : 154 - 163
  • [4] IL-12 receptor beta 2 (IL-12Rb2)-deficient mice bind IL-12 but are defective in IL-12-mediated responses
    Wu, CY
    Wang, X
    Presky, DH
    Magram, J
    FASEB JOURNAL, 2000, 14 (06): : A1182 - A1182
  • [5] Induction of Th1 autoimmune effector cells is dependent on IL-12 mediated upregulation of IL-12 receptor β2 chain expression
    Chang, JT
    Shevach, EM
    Segal, BM
    FASEB JOURNAL, 1998, 12 (04): : A307 - A307
  • [6] IL-12 receptor β2 (IL-12Rβ2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites
    Wu, CY
    Wang, X
    Gadina, M
    O'Shea, JJ
    Presky, DH
    Magram, J
    JOURNAL OF IMMUNOLOGY, 2000, 165 (11): : 6221 - 6228
  • [7] IL-12 mediated Th2 to Th1 shift in a murine model of grass allergy is associated with differential IL-12 receptor expression
    Kong, X
    Matsuse, H
    Hu, J
    Wolf, S
    Lockey, RF
    Mohapatra, SS
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 105 (01) : S180 - S180
  • [8] Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rβ1 and β2) genes and gene-gene interactions with atopic dermatitis in Koreans
    Namkung, Jung-Hyun
    Lee, Jong-Eun
    Kim, Eugene
    Kim, Song
    Kim, Sook
    Shin, Eun-Soon
    Cho, Eun-Young
    Yang, Jun-Mo
    JOURNAL OF DERMATOLOGICAL SCIENCE, 2010, 57 (03) : 199 - 206
  • [9] IL-12 receptor (IL-12R) expression and accumulation of IL-12Rβ1 and IL-12Rβ2 mRNAs in CD4+ T cells by costimulation with B7-2 molecules
    Igarashi, O
    Yamane, H
    Imajoh-Ohmi, S
    Nariuchi, H
    JOURNAL OF IMMUNOLOGY, 1998, 160 (04): : 1638 - 1646
  • [10] Systemic administration of IL-23 induces potent antitumor immunity primarily mediated through Th1-type response in association with the endogenously expressed IL-12
    Kaiga, Teruo
    Sato, Marimo
    Kaneda, Hide
    Iwakura, Yoichiro
    Takayama, Tadatoshi
    Tahara, Hideaki
    JOURNAL OF IMMUNOLOGY, 2007, 178 (12): : 7571 - 7580
12345