Relative Ultraviolet Sensitivity of Selected Antibiotic Resistance Genes in Waterborne Bacteria

被引:15
|
作者
Destiani, Rosi [1 ]
Templeton, Michael R. [1 ]
Kowalski, Wladyslaw [2 ]
机构
[1] Imperial Coll London, Dept Civil & Environm Engn, Rm 304,Skempton Bldg, London SW7 2AZ, England
[2] PurpleSun Inc, New York, NY USA
关键词
antibiotic resistance genes; disinfection; genomic modeling; UV disinfection; waterborne pathogens; DISINFECTION; DAMAGE;
D O I
10.1089/ees.2017.0179
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
This study investigated the ability of monochromatic ultraviolet (UV) light at 254nm applied at typical drinking water disinfection doses to damage the antibiotic-resistant genes mph(A), sul1, tet-A, and bla-Tem1 in waterborne bacteria. UV sensitivity rank was bla-TEM1>tet-A>sul1>mph(A), which is consistent with predictions of a previously presented genomic-based UV sensitivity model. It is the first time that predictions of the relative UV sensitivity of antibiotic resistance genes have been validated with experimental data and suggest that such modeling is useful for determining the UV sensitivity of other genes in waterborne microorganisms.
引用
收藏
页码:770 / 774
页数:5
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