TOXI 41-Strategies to obtain exposures of metabolites in preclinical species through plasma pooling and quantitative NMR in the absence of radiolabeled compounds and chemically synthesized metabolite standards

被引：0

|

作者：

Mutlib, Abdul ^{[1
]}

Vishwanathan, Karthick ^{[1
]}

Babalola, Kathlene ^{[1
]}

Wang, Jack ^{[1
]}

Espina, Robert ^{[2
]}

Yu, Linning ^{[1
]}

Adedoyin, Adedayo ^{[1
]}

Talaat, Rasmy ^{[1
]}

Scatina, JoAnn ^{[1
]}

机构：

[1] Wyeth Res, Drug Safety & Metab, Collegeville, PA 19460 USA

[2] Wyeth Res, NMR, Collegeville, PA 19426 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 238卷

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D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

41-TOXI

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页数：1

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[3] Obtaining Exposures of Metabolites in Preclinical Species through Plasma Pooling and Quantitative NMR: Addressing Metabolites in Safety Testing (MIST) Guidance without Using Radiolabeled Compounds and Chemically Synthesized Metabolite Standards
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