The Use of the OMERACT Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials

被引：6

作者：

Ammitzboll-Danielsen, Mads ^{[1
,2
]}

Ostergaard, Mikkel ^{[1
,2
]}

Naredo, Esperanza ^{[3
,4
,5
]}

Iagnocco, Annamaria ^{[6
]}

Moller, Ingrid ^{[7
]}

D'Agostino, Maria-Antonietta ^{[8
]}

Gandjbakhch, Frederique ^{[9
]}

Terslev, Lene ^{[10
]}

机构：

[1] Rigshosp, Ctr Rheumatol & Spine Dis, Copenhagen Ctr Arthrit Res COPECARE, Glostrup Nordre Ringvej 57, DK-2600 Glostrup, Denmark

[2] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark

[3] Hosp Gen Univ Gregorio Maranon, Dept Rheumatol, Madrid, Spain

[4] Univ Complutense, Madrid, Spain

[5] Hosp Univ Fdn Jimenez Diaz, Dept Rheumatol, Joint & Bone Res Unit, Madrid, Spain

[6] Univ Torino, Dipartimento Sci Clin & Biol, Turin, Italy

[7] Inst Poal Reumatol, Serv Reumatol, Barcelona, Spain

[8] Ambroise Pare Hosp, AP HP, Dept Rheumatol, Versailles, France

[9] Hop La Pitie Salpetriere, AP HP, Dept Rheumatol, Paris, France

[10] Rigshosp, Ctr Rheumatol & Spine Dis, COPECARE, Glostrup, Denmark

来源：

JOURNAL OF RHEUMATOLOGY | 2018年 / 45卷 / 02期

关键词：

ULTRASONOGRAPHY; TENOSYNOVITIS; RHEUMATOID; ARTHRITIS; OMERACT; RHEUMATOID-ARTHRITIS; DOPPLER ULTRASOUND; PROGRESSION; HAND; INFLAMMATION; SYNOVITIS; SETTINGS; WRIST; RA;

D O I：

10.3899/jrheum.170501

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. To test the sensitivity to change of the Outcome Measures in Rheumatology Clinical Trials (OMERACT) ultrasound (US) scoring system for tenosynovitis when applied in a multicenter design. Methods. RA patients with US-verified tenosynovitis were recruited when scheduled for treatment intensification. Tenosynovitis was assessed at baseline, and 3 and 6 months followup, using the semiquantitative OMERACT scoring system. Results. Expressed in median (25th; 75th percentiles), the overall greyscale and Doppler score decreased significantly from baseline at 4 (2; 7) and 3 (2; 6), to 6 months at 2 (0; 3) and 0 (0; 1, p < 0.01), respectively, and showed high responsiveness (standardized response mean >= 0.8). Conclusion. The OMERACT US scoring system for tenosynovitis showed high responsiveness, supporting its use for diagnosing and monitoring tenosynovitis in multicenter trials.

引用

页码：165 / 169

页数：5

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