A new diimide derivative from the co-culture broth of two mangrove fungi (strain no. E33 and K38)

被引：15
|
作者：
Li, Chun-Yuan [2 ]
Ding, Wei-Jia [2 ]
Shao, Chang-Lun [3 ]
She, Zhi-Gang [1 ]
Lin, Yong-Cheng [1 ]
机构：
[1] Sun Yat Sen Zhongshan Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
[2] S China Agr Univ, Coll Sci, Inst Biomat, Guangzhou 510642, Guangdong, Peoples R China
[3] Ocean Univ China, Sch Med & Pharm, Qingdao 266000, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2010年 / 12卷 / 09期
关键词：
mangrove fungi; mixed fermentation; (-)-byssochlamic acid bisdiimide; cytotoxic; semi-synthesis;
D O I：
10.1080/10286020.2010.497757
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new diimide derivative, named (2)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthesis. Primary bioassays showed that 1 had weak cytotoxic activity against Hep-2 and HepG2 cells.
引用
收藏
页码：809 / 813
页数：5
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