Miconazole mucoadhesive tablet for oropharyngeal candidiasis

被引：8
|
作者：
Lalla, Rajesh V. [1 ]
Bensadoun, Rene-Jean [2 ]
机构：
[1] Univ Connecticut, Ctr Hlth, Sect Oral Med, Dept Oral Hlth & Diagnost Sci MC1605, Farmington, CT 06030 USA
[2] CHU Poitiers, Serv Oncol Radiotherap, F-86021 Poitiers, France
来源：
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY | 2011年 / 9卷 / 01期
关键词：
Loramyc (R); miconazole mucoadhesive tablet; Oravig (TM); oropharyngeal candidiasis; ORAL CANDIDIASIS; MULTICENTER; EFFICACY; CANCER; SAFETY; TRIAL; BLIND;
D O I：
10.1586/ERI.10.152
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Oropharyngeal candidiasis is a commonly encountered problem in daily clinical practice. Topical therapies for oropharyngeal candidiasis are considered preferable to systemic therapies in most patient populations. However, traditional topical therapies have limitations including short contact time with the oral mucosa and the need for multiple doses each day. Miconazole mucoadhesive tablet has recently been approved in Europe (Loramyc (R)) and the USA (Oravig (TM)) for the treatment of oropharyngeal candidiasis. This tablet adheres to the oral mucosa and provides sustained local release of miconazole over a period of several hours with just one daily application. This article reviews the pharmacology, safety and efficacy of this novel agent.
引用
收藏
页码：13 / 17
页数：5
相关论文
共 50 条
  • [1] Development and evaluation of miconazole mucoadhesive tablets for oropharyngeal candidiasis
    Jin, Qiong
    Chen, Wei
    Wu, Wan
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2017, 16 (10) : 2325 - 2330
  • [2] Miconazole in oropharyngeal candidiasis
    Reactions Weekly, 2005, 1054 (1) : 5 - 5
  • [3] Miconazole (Oravig) for Oropharyngeal Candidiasis
    不详
    MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 2010, 52 (1352): : 95 - 96
  • [4] A Comparative Randomized, Open-label, Multicenter Study of the Efficacy and Safety of Miconazole Mucoadhesive Tablets and Miconazole Gel in the Treatment of Oropharyngeal Candidiasis [Translated Article]
    Takato, Tsuyoshi
    Kitagawa, Yoshimasa
    Kamikawa, Yoshiaki
    Kishimoto, Hiromitsu
    Nakamura, Seiji
    Komori, Takahide
    Chikazu, Daichi
    Mori, Yoshiyuki
    Tanzawa, Hideki
    Katakura, Akira
    Kanekawa, Akihiro
    Umeda, Masahiro
    Gomi, Akinori
    Yonenaga, Kazumichi
    MEDICAL MYCOLOGY JOURNAL, 2021, 62 (01) : 11 - 19
  • [5] Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis
    Van Roey, J
    Haxaire, M
    Kamya, M
    Lwanga, I
    Katabira, E
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2004, 35 (02) : 144 - 150
  • [6] Mucoadhesive In Situ Gel Formulations of Miconazole Nitrate for the Treatment of Mucosal Candidiasis
    Karavana, Sinem Y.
    Senyigit, Zeynep A.
    Hilmioglu-Polat, Suleyha
    Metin, Dilek Y.
    Zekioglu, Osman
    Baloglu, Esra
    LATIN AMERICAN JOURNAL OF PHARMACY, 2012, 31 (06): : 821 - 829
  • [7] Miconazole Nitrate Microparticles in Lidocaine Loaded Films as a Treatment for Oropharyngeal Candidiasis
    Tejada, Guillermo
    Calvo, Natalia L.
    Morri, Mauro
    Sortino, Maximiliano
    Lamas, Celina
    Alvarez, Vera A.
    Leonardi, Dario
    MATERIALS, 2023, 16 (09)
  • [8] Formulation and Evaluation of Antifungal Drug Containing Mucoadhesive Tablet for Vaginal Candidiasis
    Kanojiya, Pranita Sunil
    Wadetwar, Rita Naresh
    Godbole, Amita Prasanna
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2023, 57 (03) : S573 - S586
  • [9] Randomized, Comparative, Double-Blind, Double-Dummy, Multicenter Trial of Miconazole Buccal Tablet and Clotrimazole Troches for the Treatment of Oropharyngeal Candidiasis: Study of Miconazole Lauriad® Efficacy and Safety (SMiLES)
    Vazquez, Jose A.
    Patton, Lauren L.
    Epstein, Joel B.
    Ramlachan, Padaruth
    Mitha, Ismail
    Noveljic, Zoja
    Fourie, Jan
    Conway, Brian
    Lalla, Rajesh V.
    Barasch, Andrei
    Attali, Pierre
    HIV CLINICAL TRIALS, 2010, 11 (04): : 186 - 196
  • [10] Management of oropharyngeal candidiasis with localized oral miconazole therapy: efficacy, safety, and patient acceptability
    Collins, Curtis D.
    Cookinham, Sarah
    Smith, Jeannina
    PATIENT PREFERENCE AND ADHERENCE, 2011, 5 : 369 - 374
12345