Undernutrition is insufficiently detected in in- and outpatients, and this is likely to worsen during the next decades. The increased prevalence of obesity together with chronic illnesses associated with fat-free mass (FFM) loss will result in an increased prevalence of sarcopenic obesity. In patients with sarcopenic obesity, weight loss and the body mass index lack accuracy to detect FFM loss. FFM loss is related to increasing mortality, worse clinical outcomes, and impaired quality of life. In sarcopenic obesity and chronic diseases, body composition measurement with dual-energy X-ray absorptiometry, bioelectrical impedance analysis, or computerized tomography quantifies the loss of FFM. It allows tailored nutritional support and disease-specific therapy and reduces the risk of drug toxicity. Body composition evaluation should be integrated into routine clinical practice for the initial assessment and sequential follow-up of nutritional status. It could allow objective, systematic, and early screening of undernutrition and promote the rational and early initiation of optimal nutritional support, thereby contributing to reducing malnutrition-induced morbidity, mortality, worsening of the quality of life, and global health care costs. Copyright (C) 2011 S. Karger AG, Basel
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Univ Roma Tor Vergata, Human Physiol & Nutr Unit, Dept Syst Med, Via Montpellier 1, I-00173 Rome, ItalyUniv Roma Tor Vergata, Human Physiol & Nutr Unit, Dept Syst Med, Via Montpellier 1, I-00173 Rome, Italy
Andreoli, Angela
Garaci, Francesco
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Tor Vergata Univ, Dept Biomed & Prevent, Policlin Tor Vergata Univ Hosp, Dept Diagnost Imaging, Rome, ItalyUniv Roma Tor Vergata, Human Physiol & Nutr Unit, Dept Syst Med, Via Montpellier 1, I-00173 Rome, Italy
Garaci, Francesco
Cafarelli, Francesco Pio
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Univ Foggia, Dept Radiol, Viale Pinto 1, I-71122 Foggia, ItalyUniv Roma Tor Vergata, Human Physiol & Nutr Unit, Dept Syst Med, Via Montpellier 1, I-00173 Rome, Italy
Cafarelli, Francesco Pio
Guglielmi, Giuseppe
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Univ Foggia, Dept Radiol, Viale Pinto 1, I-71122 Foggia, Italy
Univ Foggia, Dept Radiol, Viale Luigi Pinto 1, I-71100 Foggia, Italy
IRCSS Casa Sollievo della Sofferenza, Viale Cappuccini 1, I-71013 San Giovanni Rotondo, FG, ItalyUniv Roma Tor Vergata, Human Physiol & Nutr Unit, Dept Syst Med, Via Montpellier 1, I-00173 Rome, Italy